Results 91 to 100 of about 364,775 (299)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Indefinites in Romance and beyond

Due to their flexibility in interpretation, the use of indefinites and other quantificational expressions is highly variable and subject to dynamic processes of language change.The present volume addresses fundamental linguistic questions about language 
Mensching, Guido, Lauschus, Sebastian, Rosemeyer, Malte, Enrique-Arias, Andrés, Enrique-Arias, Andés, Gutiérrez Maté, Miguel, Davatz, Jan, Stark, Elisabeth, Kellert, Olga, Becker, Martin, Francia, Marika   +10 more
core   +6 more sources

VARIATION IN PODLACHIAN INSTRUMENTAL SINGULAR ENDINGS: -OJU OR -EJU?

Filolog
This article investigates variation between the instrumental singular endings -oju and -eju in contemporary Podlachian. The phenomenon is examined against the background of East Slavic nominal morphology and analysed on the basis of a corpus of ...
Vratislav Karpišek
doaj   +1 more source

English Language Variation in Countryballs Cartoons

, 2016
Abstrak Terdapat milyaran macam bahasa di seluruh dunia yang mana beberapa diantaranya digunakan sebagai bahasa internasional untuk mempermudah masyarakat antar bangsa berkomunikasi satu sama lain.
Finsa Zulkarnain, Bachtiar
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Spatial Locative Relativization in Three African Varieties of Portuguese: Unity in Diversity and Diversity in Unity

Languages
This paper investigates the formation of spatial locative relativization in three African varieties of Portuguese. While research on relative constructions in Portuguese has deserved considerable attention in the literature, it tends to focus on the ...
Tjerk Hagemeijer, Rita Gonçalves, Nélia Alexandre   +2 more
doaj   +1 more source

Review of Rethinking Parameters

Isogloss, 2016
This is a review of the book Rethinking Parameters, edited by Luis Eguren, Olga Fernández-Soriano & Amaya Mendikoetxea. 2016. Oxford: Oxford University Press.
Samanta Planells
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Language Variations of Adolescents on Tiktok Social Media

Metathesis: Journal of English Language, Literature, and Teaching
The use of language on social media which tends to adjust its pronunciation has given rise to a phenomenon called ecrononciation. This phenomenon has been happening in Indonesia for a long time, especially among teenagers.
Siti Sulistiyarini, Gilang Tegar Prasetyo   +1 more
doaj   +1 more source

Describing Language Variation in the Colophons of Armenian Manuscripts

, 2022
Based on a sample selection of manuscript colophons, this talk explains the kind of language variation found in these texts, and describes some principles and guidelines for processing such non-Classical Armenian linguistic phenomena in the framework of ...
Van Elverdinghe, Emmanuel, Processing Language Variation: Digital Armenian (LREC 2022 workshop)   +1 more
core