Results 81 to 90 of about 1,298,540 (325)

Contact-induced variation in clausal verb complementation: the case of REGRET in World Englishes [PDF]

, 2017
It has been argued that in language contact situations both transfer processes from the substrate languages (Thomason, 2008) and cognitive effects derived from the language contact situation itself (Schneider, 2012, 2013) can constitute important ...
Romasanta, Raquel P.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Introduction to the Special Issue: Investigating Language Variation and Change in Portuguese

Languages
This Issue focuses on morphosyntactic variation and change in Portuguese [...]
Patrícia Amaral
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

When Positioning Mediates Social Judgements: Life-Stage, Gender, and Yeah-No in Australian English

Languages
This study explores the correlation between social categories and linguistic variables, focusing on the perception of the discourse marker yeah-no in Australian English.
Stacey Sherwood, Robert Mailhammer, Mark Antoniou   +2 more
doaj   +1 more source

Segregated vowels: Language variation and dialect features among Gothenburg youth–Corrigendum

Language Variation and Change, 2019
A reference appeared incorrectly in the above publication (Gross, 2019). The correct in-text citation is “(Kohn, 2018)”. The correct reference entry is “Kohn, Mary. (2018). The impact of de facto and de jure segregation on African American English in the
J. Gross
semanticscholar   +1 more source

Language Change or Language Innovation? [PDF]

, 2010
Linguists should pay special attention to those aspects of English which signal possible, impending, or ongoing change in the standard language. Not all kinds of variation will result in changes in standard English: some developments in society are ...
Dorda, Svitlana Volodymyrivna, Дорда, Светлана Владимировна, Дорда, Світлана Володимирівна   +2 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Exploring Variation and Change in the Distant Past

Cadernos de Linguística
This article explores the potential of analysing language variation and change in written records dating back to the earliest stages of the time period conventionally termed ‘historical’.
Rodrigo Hernáiz
doaj   +1 more source