Results 51 to 60 of about 278,941 (291)

Why powerful economic content and scientific language in social studies textbooks matters

open access: yesJournal of Social Science Education, 2021
• The use of scientific economic terms is insufficient in Swedish social studies textbooks. • Analysed textbooks do not offer optimal preconditions to develop in-depth economic knowledge. • Insufficient use of economic terms may have negative impact on
Niclas Modig
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Comparing Tag Scheme Variations Using an Abstract Machine Generator

open access: yes, 2008
In this paper we study, in the context of a WAM-based abstract machine for Prolog, how variations in the encoding of type information in tagged words and in their associated basic operations impact performance and memory usage.
Morales Caballero, José Francisco   +5 more
core   +1 more source

Lanskap linguistik di kelurahan Bahu kota Manado

open access: yesDiglosia
This article aims to identify and describe the phenomena of language variation, categories and functions found in Bahu sub-district, Manado city. This research method uses a qualitative descriptive method.
Jeansi Makasambe   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

PENGGUNAAN BAHASA TRANSMIGRAN JAWA DI KABUPATEN GORONTALO

open access: yesHumaniora, 2012
The  Javanese Trans migrants have come to Gorontalo district since 1953. The language used by the Trans migrants continued to be used in the place so that it becomes bilingual and even multilingual community giving rise to new phenomena.
Sayama Malabar
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Oppositions de longueur vocalique et formes canoniques dans le breton de Lanvenegen (canton du Faouët)

open access: yesLa Bretagne Linguistique, 1985
The best-known Breton is the one spoken in a large north-western half of the Breton territory. Its system has been studied in particular by François Falc'hun. Lanvénégen, a commune in Morbihan on the edge of Finistère, lies outside this area.
Erwan Evenou
doaj   +1 more source

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