Results 61 to 70 of about 278,941 (291)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Cultural Significance in Greeting Practices in Belo Dialect of the Bima Language

open access: yesRegister Journal, 2019
Indonesia is the home to a vast array of cultures and many unique languages that are the mother tongues of these various islands and cultural groups. One of these is Bima language.
Alek Alek
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Lexical organization in deaf children who use British Sign Language: Evidence from a semantic fluency task [PDF]

open access: yes, 2013
We adapted the semantic fluency task into British Sign Language (BSL). In Study 1, we present data from twenty-two deaf signers aged four to fifteen. We show that the same ‘cognitive signatures’ that characterize this task in spoken languages are also ...
Marshall, C. R.   +9 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Endurant vs perdurant : ontological motivation for language variations

open access: yes, 2016
30th Pacific Asia Conference on Language, Information and Computation, PACLIC 2016, Seoul, Republic of Korea, 28-30 October 2016Modern ontology focuses on the shared structure of knowledge representation and sheds light on underling motivations of human ...
Huang Chu-Ren, Huang, CR
core  

Variations in Business English letters written by Spanish learners

open access: yesRevista de Lenguas para Fines Específicos, 2015
Writing in a second language does not follow a fixed pattern in the different parts of the sentence or text. We can find variations in discourse due to the conceptual implications of language production.
María Luisa Carrió Pastor   +2 more
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ENGLISH LANGUAGE VARIATIONS IN WRITTEN AND ORAL TYPES OF COMMUNICATION

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2019
The article deals with the peculiarities of the English language variants functioning in the process of writing and speaking and problems of mutual understanding resulting from different variants of using English as a dominant language.
Tatyana Gennadievna Voloshina   +1 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy