Results 61 to 70 of about 23,632 (261)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Euskaldunek euskalkienganako izan dituzten jarrerez

open access: yesAnuario del Seminario de Filología Vasca "Julio de Urquijo", 1992
The aim of this essay is to gather together all accounts of the attitudes of the speakers of Basque (euskaldunes) towards the various varieties of the Basque language.
Koldo Zuazo
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Language Policy and Regional Varieties of the Korean Language

open access: yesPoliteja
The aim of this paper is to provide information on the language policy, planning, and management in the Republic of Korea. The research is focused on Standard Korean and the current state of Korean regional dialects.
Vladislava Mazana
doaj   +1 more source

De la variation au changement phonologique : une étude en synchronie dynamique du système consonantique de l’arabe parlé en Jordanie

open access: yesKervan. International Journal of Afro-Asiatic Studies, 2020
Varieties of Jordanian spoken Arabic are interesting not only because they violate the standard Arabic phonological system, but also because they exhibit innovative internal mechanisms of articulations, best be described as evolution of languages (or ...
Bassel Al Zboun, Nisreen Abu Hanak
doaj   +1 more source

Varieties and Covarieties of Languages (Extended Abstract)

open access: yesElectronic Notes in Theoretical Computer Science, 2013
AbstractBecause of the isomorphism (X×A)→X≅X→(A→X), the transition structure of a deterministic automaton with state set X and with inputs from an alphabet A can be viewed both as an algebra and as a coalgebra. This algebra-coalgebra duality goes back to Arbib and Manes, who formulated it as a duality between reachability and observability, and is ...
Jan Rutten   +2 more
openaire   +2 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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