LANGUAGE VARIETIES IN AL-AMANAH ISLAMIC MODERN COLLEGE: SEEN FROM LANGUAGE IN CONTACT
LANGUAGE VARIETIES IN AL-AMANAH ISLAMIC MODERN COLLEGE: SEEN FROM LANGUAGE IN CONTACT Miftakhul Ulum The State University of Surabaya Faculty of Languages and Arts Discipline of Language Literature miftahulum89@yahoo.co.id Slamet Setiawan The State
ULUM, MIFTAKHUL
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
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This paper explores the beliefs, attitudes, and efforts of parents with regard to the use and preservation of regional Chinese varieties including Cantonese in the region of Guangzhou, China.
Li Yaling, Li Danli, Gao Xuesong
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One Book, Two Language Varieties [PDF]
This paper presents a comparative study of alignment pairs, either contrasting expressions or stylistic variants of the same expression in the European (EP) and the Brazilian (BP) varieties of Portuguese. The alignments were collected semi-automatically using the CLUE-Aligner tool, which allows to record all pairs of paraphrastic units resulting from ...
Anabela Barreiro +4 more
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Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
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Language awareness survey among university students
In this study we examined the linguistic awareness and dialect attitudes of university students studying at the University of Nyíregyháza. It is particularly important that the future teachers have a positive attitude towards the varieties of the ...
Anita Kiss, Zita Somfalvi
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Dialectometry of Linguistic Varieties Common in the Distance between the South of Hamadan Province to the North of Khuzestan Province: Using Levenshtein Distance Approach [PDF]
Dialectometry is a computational, quantitative and statistical approach, in which linguistic differences, in a selected geographical area, are examined by using specific methods and techniques.
Shiva Piryaee +3 more
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