Results 131 to 140 of about 1,152,216 (300)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Languages, ethnicity, and education in London [PDF]

open access: yes
For the first time in 2008 the Annual School Census (ASC) required all schools to provide pupil information on the language spoken at home. Our analysis focuses on children attending state schools in London. Over 300 languages are spoken by London pupils,
Dick Wiggins   +3 more
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Des langues minoritaires en héritage. Ce que la transmission linguistique et son absence font à l’engagement militant

open access: yesEnfances, Familles, Générations
Research framework: This article is the result of doctoral work in political science. The dissertation was conducted between 2016 and 2022. It was financed by a grant from the French ministry for higher education.Objectives: The aim of this article is to
Jeanne Toutous
doaj  

Language, and Then Language . . . [PDF]

open access: yesJournal of Deaf Studies and Deaf Education, 2003
openaire   +1 more source

Sublinearly space bounded iterative arrays [PDF]

open access: yes, 2007
Iterative arrays (IAs) are a, parallel computational model with a sequential processing of the input. They are one-dimensional arrays of interacting identical deterministic finite automata.
B.S. Palano   +5 more
core  

Home - About - Disclaimer - Privacy