Results 71 to 80 of about 1,244,575 (293)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Analysis of Interdisciplinary Differences in the Structure of the Scientific Genre in the Introduction Section of Humanities Research Articles [PDF]

open access: yesپژوهشنامه علم سنجی
purpose: The purpose of this research was to analyze the genre of the introduction section of research papers in the humanities, based on John Swales' CARS model, and to demonstrate the potential interdisciplinary differences related to this model.
Roya Peyravi   +2 more
doaj   +1 more source

Putting it All Together: Agreement, Incorporation, Coordination and External Possession in Wubuy (Australia) [PDF]

open access: yes, 2010
In this paper we examine the interaction of a number of grammatical phenomena in Wubuy, a polysynthetic language from northern Australia, and show how they can be given a comprehensive analysis within the framework of LFG. While each of these phenomena ?
Baker, B   +3 more
core   +1 more source

Searching a biomedical database from Bulgaria : the ABS database [PDF]

open access: yes, 2007
The University of Sofia, Bulgaria, disseminates local biomedical literature (1994 to present) through a free online database, ABS. We systematically searched ABS to identify citations to controlled trials and find what proportion of these studies are to
Abhijnhan, A.   +3 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Can Natural Speech Prosody Distinguish Autism Spectrum Disorders? A Meta-Analysis

open access: yesBehavioral Sciences
Natural speech plays a pivotal role in communication and interactions between human beings. The prosody of natural speech, due to its high ecological validity and sensitivity, has been acoustically analyzed and more recently utilized in machine learning ...
Wen Ma, Lele Xu, Hao Zhang, Shurui Zhang
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

A tribute to Elizaveta Ubryatova: professional life and personal destiny [PDF]

open access: yes, 2015
The article was submitted on 10.06.2015. Translated by Dr. Lilia Gorelova.In Russia, the name of prominent turkologist Elizaveta Ivanovna Ubryatova, at present is known mostly to specialists who study the languages spoken by the Northern peoples of the ...
Shirobokova, N.   +1 more
core   +1 more source

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