Results 51 to 60 of about 110,015 (305)

Second Language Motivational Selves and Interactional Pragmatics in Study Abroad: A Qualitative Study

open access: yesLanguages
The effects of individual differences factors on second language (L2) pragmatic competence are of interest to researchers because the development of L2 pragmatic competence is directly related to learners’ personal traits and their knowledge of ...
Jun Lang, Feng Xiao, Minghua Zhang
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Can Trust in Climate-Skeptical Governments Inhibit Pro-Environmental Action? Implications for Public Participation and Democratic Innovations

open access: yesSocieties
In the scientific literature, being a woman and citizens’ trust are factors that are often linked to a higher frequency of pro-environmental behaviors.
Mirko Duradoni   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Hare and the King’s Daughter [PDF]

open access: yes, 2008
In this inteview Luisa Nativi performs and translates a tale about the intelligent Hare (Karamojong, Uganda)The Verba Africana series publishes video recording of African verbal arts on CDRom's, DVD’s and the Internet.
Merolla, Daniela
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Early Soviet research projects and the developments of "Bakhtinian" ideas: the view from the archives [PDF]

open access: yes, 2006
[FIRST PARAGRAPH] When the history of Bakhtin studies is finally written, one particularly ironic aspect that will stand out is that an accurate understanding of the development of dialogic ideas has required us to liberate ourselves from a series of ...
Brandist, C.
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Ideological Struggles and Identity Construction within the Politics of French Linguistics in Indonesia

open access: yesHumaniora, 2019
This article aims to analyse the ideological struggles reflected in the identity construction of French-language users in Indonesia. Using a critical sociolinguistic approach, it examines how Indonesians users, with their ideologies, adapt or adopt the ...
Merry Andriani   +2 more
doaj   +1 more source

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