Results 51 to 60 of about 45,919 (245)

THE INTERRELATIONSHIPS BETWEEN STUDENTS’ PERCEPTIONS OF FOREIGN LANGUAGE SKILLS AND INTERCULTURAL COMMUNICATIVE COMPETENCES [PDF]

open access: yesJournal of Languages for Specific Purposes, 2023
Globalisation and internationalisation have caused massive changes in several fields of life worldwide, with significant transitions in Hungary. The advent of multinational companies, including SSCs (Shared Service Centres), has impacted the labour ...
Tímea Lázár   +3 more
doaj  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Digital Environment Teaching Model for Foreign Languages for Specific Purposes

open access: yesInovacije u Nastavi, 2019
The aim of this paper is to present a digital environment teaching model, based on critically observed problems in teaching the foreign language for specific purposes and the analysis of the educational potentials of digital technologies, in the context ...
Miroslava R. Ristić
doaj   +1 more source

Language socialization in professional cultures : Language for specific purposes

open access: yesLes Cahiers de l'APLIUT, 1993
Brennan Moya, Naerssen Margaret Van. Language socialization in professional cultures : Language for specific purposes. In: Cahiers de l'APLIUT, volume 13, numéro 2, 1993. Les Langues de spécialité dans le monde. pp. 16-26.
Brennan, Moya, Naerssen, Margaret Van
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Joanna Kic-Drgas & Violeta Jurkovič: Paths of purpose: a journey into LSP teacher development. Brill, 2024.

open access: yesScripta Manent
This volume, authored by Joanna Kic-Drgas and Violeta Jurkovič, offers a comprehensive exploration of the educational and professional development of teachers specializing in languages for specific purposes (LSP).
Yasemin Kirkgöz
doaj   +1 more source

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