Results 51 to 60 of about 476 (262)

THE USE OF METALANGUAGE AMONG SECOND LANGUAGE LEARNERS TO MEDIATE L2 GRAMMAR LEARNING

open access: yesMalaysian Journal of Learning and Instruction, 2017
Purpose – This study investigated the use of metalanguage as a mediational tool in understanding targeted grammatical concepts from the perspective of the Sociocultural approach (SCT) in learning a second language (L2).
Haliza Harun   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Lian M. Madsen, Martha S. Karrebæk, and Janus S. Møller (eds.), Everyday Languaging. Collaborative Research on the Language Use of Children and Youth

open access: yesIperstoria, 2016
Recensione di Everyday Languaging. Collaborative Research on the Language Use of Children and Youth , a cura di Lian M. Madsen, Martha S.
Paola Vettorel
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Toward a Critical Multilingual Research Framework: De-Naturalizing Language(s) Through a Translanguaging Methodology

open access: yesForum: Qualitative Social Research
Language is a multi-purpose research medium, yet not neutral. Its use reveals a person's class and cultural, regional, and educational background. Scholars in migration studies should be sensitive to these social distinctions reflected in linguistic ...
Tetiana Havlin
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Languaging as Agent and Constituent of Cognitive Change in an Older Adult:An Example

open access: yesCanadian Journal of Applied Linguistics, 2011
Vygotsky’s writings have established the critical importance of language in the development of higher mental functions, including memory and attention.
Merrill Swain, Sharon Lapkin
doaj  

Find the word! --- But where? : Maturana's 'Coordination' and Sartre's 'Reflection' around Naming

open access: yesFrontiers in Psychology, 2015
‘Behavioral coordination’ theory of language of H. R. Maturana (1928- ) does not give a clear explanation for the questions of how naming takes place and where a word adequate for our experience comes from. This flaw may be alleviated by J.-P.
Seiichi eImoto
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

(Trans)languaging-for-learning: A perspective from the South

open access: yesReading & Writing
Background: While the concept of translanguaging has gained significant traction in education in multilingual contexts, it is also debated and contested.
Carolyn McKinney, Robyn Tyler
doaj   +1 more source

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