Background and aimsVonoprazan, a novel acid suppressant, has been employed in the treatment of peptic ulcer disease in recent years. However, the efficacy and safety of vonoprazan versus proton-pump inhibitors remains controversial.
Lidi Tian +4 more
doaj +1 more source
A UV-spectrophotometric method is described for the determination of lansoprazole (LAN). The method is based on the measurement of the absorbance of LAN solution in acetonitrile at 281 nm. The system obeyed Beer's law over the concentration range of 1.25-
Zenita Devi Okram +3 more
doaj +1 more source
Implications of Long-term Proton Pump Inhibitor Use: Promoting Step-Down Therapy for Management of Gastro-esophageal Reflux Disease in the Outpatient Setting [PDF]
Per the International Montreal Consensus, gastro-esophageal reflux disease (GERD) is defined as a condition which develops when the reflux of stomach contents causes troublesome symptoms or complications .
Kapadia, Sonam
core +1 more source
Possibilities for prescribing lansoprazole in the outpatient practice
Acid-dependent diseases are an urgent problem of modern gastroenterology. Antisecretory agents are first-line drugs in the treatment of this pathology, the leaders among which are proton pump inhibitors (PPI). Due to the wide representation of this group
I. G. Pakhomova, E. Yu. Pavlova
doaj +1 more source
The Use of Proton Pump Inhibitors Among Adults in Norway—A Nationwide Drug Utilization Study
A nationwide study covering the years 2009–2022 explored trends in proton pump inhibitor use and possible explanations for their increase. ABSTRACT The use of proton pump inhibitors (PPIs) has increased in Western countries over several decades, and there is concern about unsubstantiated indications and effects of long‐term use.
Reidar Fossmark +4 more
wiley +1 more source
\u3cem\u3eHelicobacter pylori\u3c/em\u3e infection in Havana, Cuba. Prevalence and \u3cem\u3ecagA\u3c/em\u3e status of the strains [PDF]
There is a great paucity of information about Helicobacter pylori infection in the countries of the Caribbean basin. Almost no studies have been performed to determine the prevalence, antibiotic resistance or virulence factors of the bacterium.
Camou-Juncas, Christine +12 more
core +1 more source
Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study [PDF]
journal ...
Ashida, Kiyoshi +7 more
core +2 more sources
The effect of lansoprazole administration during pregnancy on the placenta
Introduction: Lansoprazole is one of the proton pump inhibitor drugs widely used in the treatment of gastro-duodenal ulcers and disorders. However, there is not enough data about unexplored adverse effects of lansoprazole on the integrity of the ...
Ali Louei Monfared, Morteza Shamsi
doaj
Repositioning proton pump inhibitors as anticancer drugs by targeting the thioesterase domain of human fatty acid synthase [PDF]
Fatty acid synthase (FASN), the enzyme responsible for de novo synthesis of free fatty acids, is up-regulated in many cancers. FASN is essential for cancer cell survival and contributes to drug resistance and poor prognosis.
Fako, Valerie E. +4 more
core +5 more sources
ABSTRACT Pharmacogenomic (PGx) testing is increasingly utilized to guide psychiatric medication selection and dosing, yet real‐world characterizations of test ordering and clinical implications remain understudied. Additionally, the extent to which psychiatry‐focused PGx results inform prescribing beyond mental health medications is unclear. This study
Lusi Zhang +10 more
wiley +1 more source

