Results 41 to 50 of about 3,185,671 (263)

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Prognostic value of plasma IL-27 on biological viability of hepatic cystic echinococcosis

International Journal of Infectious Diseases, 2021
Objectives: To investigate potential biomarkers for distinguishing biological viability of hepatic cystic echinococcosis. Methods: Using Luminex assay we measured plasma concentrations of cytokine and chemokine in patients with active and non-active ...
Shadike Apaer, Hai-zhang Ma, Tao Li, Gang Yao, Qi Zeng, Jing Wu, Nuerzatijiang Anweier, Xiapukaiti Fulati, Jin-ming Zhao, Hao Wen, Tuerhongjiang Tuxun   +10 more
doaj   +1 more source

Practice, training and safety of laparoscopic surgery in low and middle-income countries.

World Journal of Gastrointestinal Surgery, 2017
Surgical management of diseases is recognised as a major unmet need in low and middle-income countries (LMICs). Laparoscopic surgery has been present since the 1980s and offers the benefit of minimising the morbidity and potential mortality associated ...
M. Alfa-Wali, S. Osaghae
semanticscholar   +1 more source

Lymph Node Metastasis Pattern and Influencing Factors in Esophageal Squamous Cell Carcinoma

AGING MEDICINE, EarlyView.
Among 388 patients with esophageal squamous cell carcinoma who underwent curative resection, 144 (37.1%) developed lymph node metastasis. Upper thoracic tumors mainly involved upper mediastinal and upper right paratracheal nodes, whereas lower thoracic tumors more often involved paracardial and abdominal nodes.
Yuheng Wang, Qingqing Ding, Lei Xue, Jinhua Luo   +3 more
wiley   +1 more source

Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation

Journal of Experimental & Clinical Cancer Research, 2023
Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor prognosis. The underlying functions and mechanisms of circular RNA and SUMOylation in the development of ICC remain poorly understood.
Junhao Zheng, Yali Wang, Liye Tao, Jingwei Cai, Zefeng Shen, Yang Liu, Haoyu Pan, Shihao Li, Yeling Ruan, Tianyi Chen, Zhengtao Ye, Kainan Lin, Yin Sun, Junjie Xu, Xiao Liang   +14 more
doaj   +1 more source

Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11

Frontiers in Oncology, 2022
ObjectiveCholangiocarcinoma (CHOL) is a deadly cancer worldwide with limited available therapies. The aim of this study was to investigate key exosomal miRNAs and their functions in CHOL development.MethodsSerum exosomes were isolated from patients with ...
Huijie Gao, Huijie Gao, Zhaobin He, Zhaobin He, Chao Gao, Chao Gao, Naiqing Liu, Zhaoyang Zhang, Zhaoyang Zhang, Weibo Niu, Weibo Niu, Jun Niu, Jun Niu, Cheng Peng, Cheng Peng   +14 more
doaj   +1 more source

Impact of Abdominoperineal Resection on Postoperative Male Sexual Function After Minimally Invasive Rectal Cancer Surgery: A Subgroup Analysis From the LANDMARC Study

Annals of Gastroenterological Surgery, EarlyView.
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara, Shinobu Ohnuma, Michiaki Unno, Masakatsu Numata, Tomohiro Yamaguchi, Koya Hida, Tomonori Akagi, Suguru Hasegawa, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Keisuke Kazama, Masanori Hotchi, Masahiko Watanabe, Takeshi Naitoh   +14 more
wiley   +1 more source

The influence of different bariatric surgeries on male sex hormones and semen parameters among infertile obese male patients: an observational study

BMC Surgery
Background This research examines the impact of bariatric procedures on male sex hormones and semen parameters in infertile men with obesity. Obesity adversely affects male fertility by causing hormonal imbalances and worsening semen quality.
Mahmoud Azhary, Mohamed Hassan Ali, Mohamed Ahmed AbdELsalam, Mohamed Elshal, Ahmed Maher Abdelmonim, Ehab Fathy Ahmed   +5 more
doaj   +1 more source

Laparoscopic surgery for T4 colon cancer: a systematic review and meta-analysis

Surgical Endoscopy, 2017
BackgroundIn colon cancer, T4 stage is still assumed to be a relative contraindication for laparoscopic surgery considering the oncological safety. The aim of this systematic review with meta-analysis was to evaluate short- and long-term oncological ...
C. Klaver, Tijmen M. Kappen, W. Borstlap, W. Bemelman, P. Tanis   +4 more
semanticscholar   +1 more source

Annual Report of the 2022 National Clinical Database: Decade‐Long Trends and Current Status of Gastroenterological Surgery in Japan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The National Clinical Database (NCD) of Japan is the largest nationwide registry, covering over 95% of surgeries in the country. This 2022 annual report summarizes the short‐term outcomes of gastroenterological surgeries and discusses trends and insights over the past decade.
Koshi Kumagai, Arata Takahashi, Hideki Ueno, Naoki Hiki, Yoshiki Kajiwara, Tomoki Ebata, Takao Otsuka, Taro Oshikiri, Yoshihiro Kakeji, Takanori Goi, Akio Saiura, Hiroshi Saeki, Chie Tanaka, Masanori Tokunaga, Tsutomu Fujii, Satoru Matsuda, Tsunekazu Mizushima, Hiroyuki Yamamoto, Yuko Kitagawa, Ken Shirabe   +19 more
wiley   +1 more source