Results 51 to 60 of about 145,859 (268)

Clinical Outcomes of Early Versus Delayed Appendectomy

Journal of Nobel Medical College
Background: Acute appendicitis is one of the most common surgical emergencies worldwide. The controversy still exists about the timing of operation for appendicitis. The aim of this study was to compare the outcomes between early appendectomy and delayed
Amit Bhattarai, Dinesh Adhikari, Aakash Kafle, Bigyan Adhikari, Aakash Mahato, Kritika Shreewastav   +5 more
doaj   +1 more source

Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation

Journal of Experimental & Clinical Cancer Research, 2023
Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor prognosis. The underlying functions and mechanisms of circular RNA and SUMOylation in the development of ICC remain poorly understood.
Junhao Zheng, Yali Wang, Liye Tao, Jingwei Cai, Zefeng Shen, Yang Liu, Haoyu Pan, Shihao Li, Yeling Ruan, Tianyi Chen, Zhengtao Ye, Kainan Lin, Yin Sun, Junjie Xu, Xiao Liang   +14 more
doaj   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

Development and internal validation of a machine learning–based model for predicting postoperative complications after primary liver cancer resection

BMC Surgery
Objective To identify risk factors for postoperative major complications after resection of primary liver cancer and to develop machine learning-based risk prediction models.
Zhang Shuo, Du Chen Hui, Zhang Qing Long, Dong Qiang, Huang Jin Chuan, Han Xu, Shadike Apaer, Cao Xin Ling   +7 more
doaj   +1 more source

Prognostic value of plasma IL-27 on biological viability of hepatic cystic echinococcosis

International Journal of Infectious Diseases, 2021
Objectives: To investigate potential biomarkers for distinguishing biological viability of hepatic cystic echinococcosis. Methods: Using Luminex assay we measured plasma concentrations of cytokine and chemokine in patients with active and non-active ...
Shadike Apaer, Hai-zhang Ma, Tao Li, Gang Yao, Qi Zeng, Jing Wu, Nuerzatijiang Anweier, Xiapukaiti Fulati, Jin-ming Zhao, Hao Wen, Tuerhongjiang Tuxun   +10 more
doaj   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

BJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro, J. H. Kauppila, S. Markar, A. Johar, P. Lagergren   +4 more
wiley   +1 more source

Laparoscopic Colorectal Surgery [PDF]

The Permanente Journal, 2008
Laparoscopic colon resections are being performed with increasing frequency in the United States, though the use of minimally invasive techniques in colorectal surgery has lagged behind its application in other surgical fields. Since the first laparoscopic colectomy was described in 1991, a great deal of controversy has surrounded its use, particularly
openaire   +2 more sources

EndoTac: An Endoscopic Camera‐Based Tactile Sensor with High Sensitivity for Minimally Invasive Surgery

Advanced Science, EarlyView.
EndoTac presents a trocar‐compatible endoscopic vision‐based tactile sensor that uses a convex mirror to enlarge side‐facing tactile coverage during minimally invasive vessel palpation. Distorted tactile images are unwarped and processed by a learning model to estimate vascular deformation, enabling sensitive, spatially distributed tactile perception ...
Yupeng Wang, Nicolas Raison, Xuyang Zhang, Aijia Yang, Lukas Lindenroth, Shan Luo   +5 more
wiley   +1 more source

Syncope with Surprise: An Unexpected Finding of Huge Gastric Diverticulum

Case Reports in Surgery, 2016
A gastric diverticulum is a pouch protruding from the gastric wall. The vague long clinical history ranging between dyspepsia, postprandial fullness, and upper gastrointestinal bleeding makes this condition a diagnostic challenge.
Mauro Podda, Jenny Atzeni, Antonio Messina Campanella, Alessandra Saba, Adolfo Pisanu   +4 more
doaj   +1 more source