Computational Drug Repurposing for Alzheimer's Disease via Sheaf Theoretic Population-Scale Analysis of snRNA-Seq Data. [PDF]
Cottrell S +4 more
europepmc +1 more source
ABSTRACT Purpose To evaluate quantitative susceptibility mapping (QSM) beyond the brain through realistic simulations and to explore preliminary evidence that may be indicative of hypoxia in skull base chordomas (SBC). Methods Each step of the QSM pipeline was optimized within an in silico framework consisting of (i) phase unwrapping, (ii) background ...
P. Fenech +8 more
wiley +1 more source
Graph-Enhanced Expectation Maximization for Emission Tomography. [PDF]
Kasai R, Otsuka H.
europepmc +1 more source
RF‐Shielding of Laser‐Cut Venous Stents: Calculations, Simulations, and Experiments
ABSTRACT Purpose To develop an analytical model of the RF‐shielding of laser‐cut venous stents for different orientations and stent geometries. Methods Laser‐cut venous stents are modeled as a grid composed of circular and rectangular loops. As these loops are orthogonal they shield different components of the transmit RF field.
Lisa Regler +7 more
wiley +1 more source
This study investigates the effect of cerebral and vascular (beta‐amyloid) Aβ on regional myeloarchitecture and lipid composition in a murine model of Alzheimer's disease (AD). The study highlights the feasibility of quantitative MRI and chemical exchange saturation transfer (CEST) imaging to identify multiple biophysical mechanisms involved in ...
Syed Salman Shahid +7 more
wiley +1 more source
EFDepth: A Monocular Depth Estimation Model for Multi-Scale Feature Optimization. [PDF]
Liu F +5 more
europepmc +1 more source
Defining Scales of Field Studies and Experiments to Assess Marine Cloud Brightening
Abstract Solar radiation modification (SRM) is being discussed as a potential option for addressing climate risks while atmospheric greenhouse gas concentrations are reduced to lower levels. However, understanding of the potential efficacy, impacts, benefits and harms of different SRM approaches remains limited.
Sarah J. Doherty +3 more
wiley +1 more source
Assessment of Radiographic Image Texture in the Maxilla and Mandible Around Titanium Inserts Used for Osteosynthesis of Dentofacial Deformities. [PDF]
Antonowicz B +6 more
europepmc +1 more source
An Effective Physics‐Informed Neural Operator Framework for Predicting Wavefields
Abstract Solving the wave equation is fundamental for many geophysical applications. However, numerical solutions of the Helmholtz equation face significant computational and memory challenges. Therefore, we introduce a physics‐informed convolutional neural operator (CNO) (PICNO) to solve the Helmholtz equation efficiently.
X. Ma, T. Alkhalifah
wiley +1 more source
Symmetrization and the rate of convergence of semigroups of holomorphic functions
Abstract Let (ϕt)$(\phi _t)$, t⩾0$t\geqslant 0$, be a semigroup of holomorphic self‐maps of the unit disk D$\mathbb {D}$. Let Ω$\Omega$ be its Koenigs domain and τ∈∂D$\tau \in \partial \mathbb {D}$ be its Denjoy–Wolff point. Suppose that 0∈Ω$0\in \Omega$ and let Ω♯$\Omega ^\sharp$ be the Steiner symmetrization of Ω$\Omega$ with respect to the real axis.
Dimitrios Betsakos +1 more
wiley +1 more source

