Results 161 to 170 of about 631,512 (303)

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

Experimental demonstration of single-mode large mode area multi-trench fiber for UV-VIS light transmission

Step-index optical fibers are widely used waveguides for light transmission. However, non-linear effects are always a severe challenge for optical fibers with increasing power level.
Alam, S.U., Barua, P., Jain, D., Jung, Y., Sahu, J.K.   +4 more
core  

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Machine Learning-Assisted Burst Femtosecond Laser Polishing of Invar Alloy: Process Optimization and Performance Enhancement. [PDF]

Nanomaterials (Basel)
Lin J, Li D, Luo J, Li K, Jia X, Wang C, Li X, Sun K, Duan J.   +8 more
europepmc   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Combustion and Pyrolysis EA-IRMS Techniques to Determine the δ²H of Diamonds. [PDF]

Rapid Commun Mass Spectrom
Fourel F, Lécuyer C, Thomassot E, Deloule E, Ojeimi C.   +4 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Polarization-Insensitive Electro-Optic Modulator for the Terahertz Regime Enabled by a Graphene-Hybrid Plasmonic Waveguide. [PDF]

Nanomaterials (Basel)
Zhou X, Liu C, Li Y, Weng T, Tan Q, Huang X, Pan J.   +6 more
europepmc   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Dual-resolution megahertz optical coherence tomography prototype rectoscope for enhanced visualization of colorectal microstructures. [PDF]

J Biomed Opt
Burhan S, Schulte B, Göb M, Singh AP, Mustafa B, Lotz S, Draxinger W, Lamminger P, Saker Y, Eixmann T, Ahrens M, Heimke M, Heinze T, Wedel T, Rahlves M, Ellrichmann M, Huber R.   +16 more
europepmc   +1 more source