Results 181 to 190 of about 618,573 (283)

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Breaking dense integration limits: inverse-designed lithium niobate multimode photonic circuits. [PDF]

Nat Commun
Han X, Jiang H, He J, Zhu Z, Su J, Low MX, Jiang Y, He Y, Feng L, Nguyen TG, Boes A, Pan C, Ren G, Zhang Y, Ren X, Tian Y, Mitchell A, Xia H.   +17 more
europepmc   +1 more source

High-Energy Four-Wave Mixing, with Large-Mode-Area Higher-Order Modes in Optical Fibres [PDF]

, 2012
Chen, Y., Crozier, K., Demas, J. D., Ellenbogen, T., Grogan, M. D. W., Ramachandran, S., Rishøj, Lars Søgaard, Rottwitt, Karsten, Steinvurzel, P. E., Yan, L.   +9 more
core   +2 more sources

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Resonance-free Fabry-Pérot cavity via unrestricted orbital-angular-momentum ladder-up. [PDF]

Nat Commun
Yaraghi S, Mhibik O, Yessenov M, Miller JK, Parto M, Johnson EG, Abouraddy AF, Divliansky I.   +7 more
europepmc   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Enhanced radiative cooling by large aerosol particles from wildfire-driven thunderstorms. [PDF]

Sci Adv
Li Y, Dykema JA, Peterson DA, Feng X, Shen X, June NA, Fromm MD, McHardy TM, Jacquot JL, Pittman JV, Daube BC, Wofsy SC, Dean-Day J, Rapp AD, Bowman KP, Cziczo DJ, Mickley LJ, Pierce JR, Keutsch FN.   +18 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

High Demand Loading Conditions and Their Effect on Polyethylene Stresses in Lumbar Total Joint Replacement: Implications for Spine Wear Protocols. [PDF]

J Orthop Res
Kurtz SM, Rundell SA, Spece H, Siskey RL, Yarbrough RV.   +4 more
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source