Results 51 to 60 of about 2,796,396 (258)

Characteristics and Laser Performance of Yb3+-Doped Silica Large Mode Area Fibers Prepared by Sol–Gel Method

open access: yesFibers, 2013
Large-size 0.1 Yb2O3–1.0 Al2O3–98.9 SiO2 (mol%) core glass was prepared by the sol–gel method. Its optical properties were evaluated. Both large mode area double cladding fiber (LMA DCF) with core diameter of 48 µm and large mode area photonic crystal ...
Shikai Wang   +7 more
doaj   +1 more source

Al2O3/GeO2/P2O5/F-Doped Silica Large-Mode-Area Optical Fibers for High-Power Single-Frequency Radiation Delivery

open access: yesPhotonics, 2023
A new design of a passive optical fiber waveguide with a large mode area (LMA) and strong stimulated Brillouin scattering (SBS) suppression is proposed. The fiber core consists of two parts: a central one, doped with Al2O3 and GeO2, and a peripheral one,
Sergey Tsvetkov   +7 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Theoretical analysis of the SRS-induced mode distortion in large-mode area fiber amplifiers.

open access: yesOptics Express, 2018
In this paper, the spectral evolution properties of different transverse modes with the stimulated Raman scattering (SRS) effect are analyzed in large-mode-area (LMA) fiber amplifiers for the first time.
W. Liu   +4 more
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Anticrossing and Mode Coupling in Bent All-Glass Leakage Channel Microstructured Optical Fibers with Large Mode Area

open access: yesPhotonics
This paper presents the results of a detailed theoretical study of the bending properties of original all-glass leakage channel microstructured optical fibers (LC MOFs) over a bending radius range from 3 cm to 11 cm.
Alexander N. Denisov   +2 more
doaj   +1 more source

115  W fiber laser with an all solid-structure and a large-mode-area multicore fiber.

open access: yesOptics Letters, 2018
We investigate mode-area scaling by means of supermode operation in an all-solid multicore fiber. To obtain a large-mode area (LMA), we designed and fabricated an active double-clad multicore fiber, where each ytterbium-doped core is 19 μm in diameter ...
J. Ji   +9 more
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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