Results 111 to 120 of about 47,295 (298)

Communicating global climate change using simple indices: An update [PDF]

, 2011
Previous studies have shown that there are several indices of global-scale temperature variations, in addition to global-mean surface air temperature, that are useful for distinguishing natural internal climate variations from anthropogenic climate ...
Frank Drost, David Karoly, Karoly, D, Drost, F, Braganza, K, Karl Braganza   +5 more
core   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Multiscale Spatio-Temporal Changes of Precipitation Extremes in Beijing-Tianjin-Hebei Region, China during 1958–2017

Atmosphere, 2019
In this study, based on daily precipitation records during 1958−2017 from 28 meteorological stations in the Beijing-Tianjin-Hebei (BTH) region, the spatio-temporal variations in precipitation extremes defined by twelve indices are analyzed by the ...
Xiaomeng Song, Xianju Zou, Chunhua Zhang, Jianyun Zhang, Fanzhe Kong   +4 more
doaj   +1 more source

Hamiltonian distributed chaos and predictability in large-scale climate dynamics

, 2019
It is shown that the large-scale climate dynamics, represented by the daily indices of the North Atlantic (NAO), Pacific/North American (PNA), Arctic (AO) and Antarctic (AAO) oscillations, Asian-Australian Monsoons (ISM, WNPM and AUSM) and El Nino/La ...
Alexander Bershadskii
core   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Large-Scale Atmospheric Forcing Influencing the Long-Term Variability of Mediterranean Heat and Freshwater Budgets: Climatic Indices

Journal of Hydrometeorology, 2014
Abstract Interannual to interdecadal precipitation P, evaporation E, freshwater budget (E − P), and air–sea net heat flux Q have been correlated with the North Atlantic Oscillation (NAO), eastern Atlantic (EA), eastern Atlantic–western Russia (EA-WR), and Mediterranean Oscillation (MO) climatic indices to explore the influence of ...
Criado-Aldeanueva, Francisco, Soto-Navarro, Francisco Javier, García-Lafuente, Jesús   +2 more
openaire   +3 more sources

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source

The effects of climate and habitat on Butterfly populations

, 2006
Biodiversity is threatened globally and there is a need to monitor and understand future changes. Rigourous assessment of trends in insect populations is difficult because they are a species-rich, yet little known taxa.
Roy, David
core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source