Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Extraction of relations between genes and diseases from text and large-scale data analysis: implications for translational research. [PDF]
BMC Bioinformatics, 2015 Bravo À +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Proton pump inhibitors in systemic sclerosis: should we exercise caution? Insights from a large-scale data analysis. [PDF]
Clin RheumatolTskhakaia I +5 more
europepmc +1 more source
Weekday affects attendance rate for medical appointments: large-scale data analysis and implications. [PDF]
PLoS One, 2012 Ellis DA, Jenkins R.
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Editorial: Emerging trends in large-scale data analysis for neuroscience research. [PDF]
Front NeuroinformNathoo FS, Krigolson OE, Wang F.
europepmc +1 more source
QAPgrid: a two level QAP-based approach for large-scale data analysis and visualization. [PDF]
PLoS One, 2011 Inostroza-Ponta M +2 more
europepmc +1 more source