Results 131 to 140 of about 3,127,622 (352)

Structural and evolutionary tunnels of pairwise residue-interaction symmetries connect different structural classes of proteins [PDF]

open access: yesarXiv, 2013
Studying all non-redundant proteins in 76 most-commonly found structural domains, the present work attempts to decipher latent patterns that characterize acceptable and unacceptable symmetries in residue-residue interactions in functional proteins.
arxiv  

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Improvements on a Unified Dark Matter Model

open access: yesOpen Astronomy, 2016
We study, by means of a spherical collapse model, the effect of shear, rotation, and baryons on a generalized Chaplygin gas (gCg) dominated universe. We show that shear, rotation, and the presence of baryons slow down the collapse compared to the simple ...
Del Popolo A., Lee Xi-Guo
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

The Surface Density of Haloes

open access: yesOpen Astronomy, 2016
We study the correlation between the central surface density and the core radius of the dark matter haloes of galaxies and clusters of galaxies. We find that the surface density within the halo characteristic radius r* is not a universal quantity as ...
Del Popolo A., Lee Xi-Guo
doaj   +1 more source

The universal Associative envelope of the anti-Jordan triple system of $n \times n$ matrices [PDF]

open access: yesarXiv, 2013
We show that the universal associative enveloping algebra of the simple anti-Jordan triple system of all $n \times n$ matrices $(n \ge 2)$ over an algebraically closed field of characteristic 0 is finite dimensional. We investigate the structure of the universal envelope and focus on the monomial basis, the structure constants, and the center.
arxiv  

The Impact of Baryons on the Large-Scale Structure of the Universe

open access: yes, 2017
Numerical simulations play an important role in current astronomy researches. Previous dark-matter-only simulations have represented the large-scale structure of the Universe. However, nowadays, hydro-dynamical simulations with baryonic models, which can directly present realistic galaxies, may twist these results from dark-matter-only simulations.
Weiguang Cui, Youcai Zhang
openaire   +5 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

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