Results 41 to 50 of about 430,537 (306)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Observed Evidence for the Primordial Origin of Galaxy Sizes

open access: yesThe Astrophysical Journal
We present observational evidence supporting the scenario that the protogalactic angular momenta play an important role in molding the optical sizes of present galaxies. Analyzing the NASA-Sloan Atlas catalog in the redshift range of 0.02 ≤ z  
Jun-Sung Moon, Jounghun Lee
doaj   +1 more source

The Line-of-Sight Analysis of Spatial Distribution of Galaxies in the COSMOS2015 Catalogue

open access: yesUniverse, 2020
New observations of high-redshift objects are crucial for the improvement of the standard ΛCDM cosmological model and our understanding of the Universe.
Maxim Nikonov   +4 more
doaj   +1 more source

Machine-learning Cosmology from Void Properties

open access: yesThe Astrophysical Journal, 2023
Cosmic voids are the largest and most underdense structures in the Universe. Their properties have been shown to encode precious information about the laws and constituents of the Universe.
Bonny Y. Wang   +3 more
doaj   +1 more source

Systematic Effects on the Genus Topology of Large Scale Structure of the Universe

open access: yes, 2014
Large-scale structure of the universe is a useful cosmological probe of the primordial non-Gaussianity and the expansion history of the universe because its topology does not change with time in the linear regime in the standard paradigm of structure ...
Choi, Yun-Young   +6 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A New Wavelet Scattering Transform-based Statistic for Cosmological Analysis of Large-scale Structure

open access: yesThe Astrophysical Journal
Large-scale structure (LSS) analysis in galaxy surveys is a powerful cosmological probe but is limited by tracer bias, which can obscure underlying information and weaken parameter constraints.
Zhujun Jiang   +8 more
doaj   +1 more source

The CAMELS Project: Expanding the Galaxy Formation Model Space with New ASTRID and 28-parameter TNG and SIMBA Suites

open access: yesThe Astrophysical Journal, 2023
We present CAMELS-ASTRID, the third suite of hydrodynamical simulations in the Cosmology and Astrophysics with MachinE Learning (CAMELS) project, along with new simulation sets that extend the model parameter space based on the previous frameworks of ...
Yueying Ni   +14 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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