Results 1 to 10 of about 8,252,758 (233)
Imaging in Large Vessel Vasculitis—A Narrative Review [PDF]
J Clin MedVasculitis refers to a group of rare conditions characterized by the inflammation of blood vessels, affecting multiple systems. It presents a diagnostic and therapeutic challenge due to its broad clinical manifestations. Vasculitis is classified based on
Ioana Popescu +13 more
semanticscholar +3 more sources
Pathogenic Role of Monocytes/Macrophages in Large Vessel Vasculitis
Frontiers in Immunology, 2022 Vasculitis is an autoimmune vascular inflammation with an unknown etiology and causes vessel wall destruction. Depending on the size of the blood vessels, it is classified as large, medium, and small vessel vasculitis.
Ryu Watanabe, Motomu Hashimoto
exaly +4 more sources
Janus Kinase inhibitors in the treatment of large vessel vasculitis: a systematic review and meta-analysis [PDF]
Open MedicineThis meta-analysis evaluates Janus Kinase (JAK) inhibitors’ efficacy and safety in large vessel vasculitis (LVV), encompassing Giant Cell Arteritis (GCA) and Takayasu’s Arteritis (TAK).
Bai Yang, Wang Zhe, Zhang Chunling
doaj +3 more sources
Vasculitogenic T Cells in Large Vessel Vasculitis
Frontiers in Immunology, 2022 Vasculitis is an autoimmune disease of unknown etiology that causes inflammation of the blood vessels. Large vessel vasculitis is classified as either giant cell arteritis (GCA), which occurs exclusively in the elderly, or Takayasu arteritis (TAK), which
Ryu Watanabe, Motomu Hashimoto
doaj +2 more sources
Nature Reviews Disease Primers, 2021 Large-vessel vasculitis is the most common primary vasculitis in adults, manifesting as inflammation of the aorta and its major branches. This Primer reviews the epidemiology, pathophysiology, diagnosis and management of this disease, highlights its ...
D. Pugh +12 more
exaly +2 more sources
A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim
Case Reports in Oncological Medicine, 2022 Checkpoint inhibitors (CPIs) and pegfilgrastim, a long-acting growth factor agent, are vital components of current cancer treatments. Immune-related adverse events (irAEs) such as colitis and pneumonitis are well-established toxicities associated with ...
Joseph Mort +6 more
doaj +2 more sources
Perspectives of JAK Inhibitors for Large Vessel Vasculitis
Frontiers in Immunology, 2022 Vasculitis is an inflammation of the blood vessels caused by autoimmunity and/or autoinflammation, and recent advances in research have led to a better understanding of its pathogenesis. Glucocorticoids and cyclophosphamide have long been the standard of
Ryu Watanabe, Motomu Hashimoto
doaj +2 more sources
Large-vessel vasculitis and Q fever correlation [PDF]
European Journal of Case Reports in Internal Medicine, 2023 Q fever is a zoonotic infection caused by the pathogen Coxiella burnetii, and patients can present with a wide spectrum of clinical manifestations, depending on whether it is an acute or a chronic infection. We present the case of a 61-year-old male with
Joana C. Ramos +2 more
doaj +2 more sources
Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling [PDF]
Arthritis RheumatolTakayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments.
R. T. Maughan +15 more
semanticscholar +2 more sources
Virus and Autoimmunity: Can SARS-CoV-2 Trigger Large Vessel Vasculitis?
European Journal of Case Reports in Internal Medicine, 2022 Introduction: Viral infections can induce autoimmune diseases in susceptible patients. SARS-CoV-2 has been associated with the development of rheumatic disease, especially small vessel vasculitis and arthritis. Typically, onset occurs days to weeks after
João Lázaro Mendes +4 more
doaj +2 more sources