Results 21 to 30 of about 8,252,758 (233)

Vasculitis: From Target Molecules to Novel Therapeutic Approaches

Biomedicines, 2021
Systemic vasculitis is a group of diverse diseases characterized by immune-mediated inflammation of blood vessels. Current treatments for vasculitis, such as glucocorticoids and alkylating agents, are associated with significant side effects. In addition,
Sang-Wan Chung
doaj   +1 more source

Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis

Journal of the American College of Cardiology, 2023
Background Assessing inflammatory disease activity in large vessel vasculitis (LVV) can be challenging by conventional measures. Objectives We aimed to investigate somatostatin receptor 2 (SST2) as a novel inflammation-specific molecular imaging target ...
A. Ćorović, C. Wall, M. Nus, D. Gopalan, Yuan Huang, M. Imaz, M. Zulcinski, M. Peverelli, A. Uryga, Jordi Lambert, D. Bressan, R. Maughan, C. Pericleous, S. Dubash, N. Jordan, D. Jayne, S. Hoole, P. Calvert, A. Dean, D. Rassl, T. Barwick, M. Iles, M. Frontini, G. Hannon, R. Manavaki, T. Fryer, L. Aloj, M. Graves, F. Gilbert, M. Dweck, D. Newby, Z. Fayad, G. Reynolds, Ann W. Morgan, E. Aboagye, A. Davenport, H. Jørgensen, Z. Mallat, M. Bennett, J. Peters, J. Rudd, J. Mason, J. Tarkin   +42 more
semanticscholar   +1 more source

Zoledronate-Induced Large Vessel Vasculitis Diagnosed by PET/CT

Journal of Vascular Diseases, 2023
Bisphosphonates remain a first-line treatment for osteoporosis. The most-widely used is zoledronate, which is well tolerated by most patients, but may rarely cause acute inflammatory reactions, which resemble those of large vessel vasculitis (LVV).
Dmitry Shchekochikhin, Olga Vinogradskaya, Evgeniia Bublik, Maria Shmyreva, Gregory Koroba, Alexander Farmanov, Irakliy Aslanidis, Diana Pursanova, Veronica Manukova, Alexey Zilov, Alexey Zhivov   +10 more
doaj   +1 more source

Role of 18F-FDG PET/CT in Large Vessel Vasculitis and Polymyalgia Rheumatica

Journal of Nuclear Medicine, 2023
Systemic vasculitides comprise a group of autoimmune diseases affecting blood vessels, including large vessel vasculitis (LVV) and medium-sized vessel vasculitis such as giant cell arteritis (GCA) and Takayasu arteritis (TAK).
R. Slart, P. Nienhuis, A. Glaudemans, E. Brouwer, O. Gheysens, K. V. D. Van der Geest   +5 more
semanticscholar   +1 more source

Role of Neutrophils in Systemic Vasculitides

Frontiers in Immunology, 2020
Neutrophils and neutrophil extracellular traps (NETs) contribute to the pathogenesis of many autoimmune diseases, including vasculitis. Though neutrophils, and NETs, can break self-tolerance by being a source of autoantigens for autoantibodies in anti ...
Despina Michailidou, Tomas Mustelin, Christian Lood   +2 more
doaj   +1 more source

Diagnostic value of [18F]FDG-PET/CT for treatment monitoring in large vessel vasculitis: a systematic review and meta-analysis

European Journal of Nuclear Medicine and Molecular Imaging, 2021
Monitoring disease activity in patients with large vessel vasculitis (LVV) can be challenging. [18F]FDG-PET/CT is increasingly used to evaluate treatment response in LVV.
K. V. D. Van der Geest, G. Treglia, A. Glaudemans, E. Brouwer, M. Sandovici, F. Jamar, O. Gheysens, R. Slart   +7 more
semanticscholar   +1 more source

LB0009 EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice: 2023 update

Annals of the Rheumatic Diseases, 2023
Imaging recommendations for primary large vessel vasculitis (LVV) were developed in 2018. Several new studies have emerged since then, and an update of the original statements was required.To update the recommendations for the use of imaging in LVV.A ...
C. Dejaco, S. Ramiro, M. Bond, P. Bosch, C. Ponte, S. Mackie, T. Bley, D. Blockmans, S. Brolin, E. C. Bolek, R. Cassie, M. C. Cid, J. Collada, B. Dasgupta, B. Nielsen, E. de Miguel, H. Direşkeneli, C. Duftner, A. Hočevar, A. Moltó, V. Schäfer, L. Seitz, R. Slart, W. Schmidt   +23 more
semanticscholar   +1 more source

Spectrum of Large- and Medium-Vessel Vasculitis in Adults: Neoplastic, Infectious, Drug-Induced, Autoinflammatory, and Primary Immunodeficiency Diseases [PDF]

, 2022
PURPOSE OF REVIEW: To provide a comprehensive review of drugs and neoplastic, infectious, autoinflammatory, and immunodeficiency diseases causing medium- to large-vessel vasculitis in adults with emphasis on information essential for the initial ...
Recher, Mike, Fabian Lötscher, Pop, Roxana, Seitz, Pascal, Mike Recher, Luca Seitz, Seitz, Luca, Pascal Seitz, Lötscher, Fabian, Roxana Pop   +9 more
core   +2 more sources

New Therapeutic Approaches to Large-Vessel Vasculitis.

Annual Review of Medicine, 2023
Giant cell arteritis (GCA) and Takayasu arteritis (TAK) are large-vessel vasculitides affecting the aorta and its branches. Arterial damage from these diseases may result in ischemic complications, aneurysms, and dissections.
M. Kaymakci, K. Warrington, T. Kermani
semanticscholar   +1 more source

Neutrophil extracellular trap formation in anti-neutrophil cytoplasmic antibody-associated and large-vessel vasculitis

Clinical Immunology, 2023
Levels of neutrophil extracellular traps (NETs) were measured in plasma of healthy controls (HC, n=30) and patients with granulomatosis with polyangiitis (GPA, n=123), microscopic polyangiitis (MPA, n=61), Takayasu’s arteritis (TAK, n=58), and giant cell
Despina Michailidou, R. Kuley, Ting Wang, Payton Hermanson, P. Grayson, D. Cuthbertson, N. Khalidi, C. Koening, C. Langford, Carol A. McAlear, L. Moreland, C. Pagnoux, P. Seo, U. Specks, A. Sreih, K. Warrington, P. Monach, P. Merkel, C. Lood   +18 more
semanticscholar   +1 more source