Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source
Acute Perforated Large Bowel Obstruction Due to Colorectal Malignancy: A Surgical Emergency With Options. [PDF]
Ikizoglu M, Sahagian M, Roy J, Rhee P.
europepmc +1 more source
Large Bowel Obstruction Secondary to Urinary Retention. [PDF]
Kimia Yavari S, Pourafkari L.
europepmc +1 more source
Synchronous volvulus of the sigmoid colon and caecum, a very rare cause of large bowel obstruction
Shariful Islam +3 more
openalex +2 more sources
Pseudo-obstruction of the large bowel. [PDF]
P K Caves, H. Alan Crockard
openalex +1 more source
IMPROVING CONSPICUITY OF THE CANINE GASTROINTESTINAL WALL USING DUAL PHASE CONTRAST-ENHANCED COMPUTED TOMOGRAPHY: A RETROSPECTIVE CROSS-SECTIONAL STUDY [PDF]
Balthazar +24 more
core +2 more sources
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Double Large Gallstones Ileus: An Unusual Cause of Mechanical Large Bowel Obstruction. [PDF]
Kalu U, Ansari A, Maheshwari G, Joshi S.
europepmc +1 more source
A 47-Year-Old Man with Hyperphosphatemia Due to Chronic Renal Failure Treated with Lanthanum Carbonate Tablets Presenting Acutely with Partial Large Bowel Obstruction. [PDF]
Zhou Q +5 more
europepmc +1 more source

