Results 71 to 80 of about 209,931 (313)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A discrete approach to continuum economies [PDF]
We consider a perfectly competitive economy in which only a finite number of different agents' characteristics can be distinguished. We associate this economy with an n-agents' economy with an ordered Banach commodity space, and we prove that the ...
García Cutrín, Javier +1 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Strategic equilibrium in economies with a continuum of agents [PDF]
In this note, a pure exchange economy with a continuum of agents who behave strategically in endowments and preferences is considered. A notion of equilibrium, namely, strategic equilibrium is defined. It is shown that price-taking and strategic behavior
Moreno García, Emma +1 more
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The Claw: An Avian-Inspired, Large Scale, Hybrid Rigid-Continuum Gripper
Most robotic hands have been created at roughly the scale of the human hand, with rigid components forming the core structural elements of the fingers. This focus on the human hand has concentrated attention on operations within the human hand scale, and
Mary E. Stokes +4 more
doaj +1 more source
Measuring club-sequences with a large continuum
15 ...
Asperó, David, Mota, Miguel Angel
openaire +2 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Nash Equilibria of Games with a Continuum of Players [PDF]
We characterize Nash equilibria of games with a continuum of players (Mas-Colell (1984)) in terms of approximate equilibria of large finite games. For the concept of $(\epsilon,\epsilon)$ - equilibrium --- in which the fraction of players not $\epsilon$ -
Guilherme Carmona
core
Numerical simulation of continuum generation in a multimode nonlinear waveguide
Continuum generation in large multimode nonlinear waveguides offers the exciting prospect of a new generation of compact, integrated, and high-power broadband light sources. Recently a novel technique based on Scanning Near-field Optical Microscopy (SNOM)
Horak, P. +7 more
core +1 more source

