Results 131 to 140 of about 13,006,447 (294)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Day-ahead optimal scheduling of active distribution networks considering security constraints via transmission-distribution coordination

Frontiers in Energy Research
High penetration of distributed renewable energy sources in distribution networks, if optimized solely for self-economic benefits, can lead to node voltage violations and exacerbate the peak-shaving burden on the power grid.
Wanming Zhang, Yuanyuan Bi, Tianwei Pei, Yuanyi Zhang, Baiyang Zhang, Botong Liu   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Research on Calculation Method of On-Orbit Instrumental Line Shape Function for the Greenhouse Gases Monitoring Instrument on the GaoFen-5B Satellite

Remote Sensing
The Greenhouse Gases Monitoring Instrument is based on the spectroscopic principle of spatial heterodyne spectroscopy technology and has the characteristics of no moving parts, a hyperspectral resolution, and a large luminous flux.
Yunfei Han, Hailiang Shi, Haiyan Luo, Zhiwei Li, Hanhan Ye, Chao Li, Yi Ding, Shichao Wu, Xianhua Wang, Wei Xiong, Chenhui Hou   +10 more
doaj   +1 more source

The local limit theorem of large deviations for multiplicative functions

Lietuvos matematikos rinkinys, 2001
In the present paper we continue investigation of the local distribution of multiplicative ari­thmetic functions from the class M(G). A local theorem of large deviations is obtained.
openaire   +3 more sources

A Note on Numerical Estimation of Sato’s Two-Level CES Production Function [PDF]

In this paper Sato’s two-level CES production function has been estimated by nonlinear regression carried out through five different methods of optimization, namely, the Hooke-Jeeves Pattern Moves (HJPM), the Hooke-Jeeves-Quasi-Newton (HJQN), the ...
Mishra, SK
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Prediction method of TBM excavation axis deviation for small turning tunnels based on LSTM neural network

Meitan xuebao
During the construction of full face tunnel boring machine (TBM), due to the influence of geological environment, personnel operation, equipment itself and other factors, it is easy to cause large deviation between TBM boring route and design axis ...
Lijie DU, Hongda HAO, Qingwei LI, Yalei YANG, Weidong ZHANG, Jiayi LIU, Hongchao FENG   +6 more
doaj   +1 more source

On the Probability of Large Deviations of Functions of Several Empirical CDF'S

The Annals of Mathematical Statistics, 1967
In [14], Sanov proved that if $F_N$ is the empirical cumulative distribution function (cdf) of a sample drawn from a population whose true cdf is $F_0$ and $\Omega$ is a set of cdf's which satisfies certain regularity conditions and does not contain $F_0$, then $P\{F_N \epsilon \Omega\}$ is roughly $\exp \{-N \inf_{F\epsilon \Omega} \int \ln (dF/dF_0 ...
openaire   +2 more sources