Results 91 to 100 of about 8,481,699 (293)
Guiding Principle for Minor-Embedding in Simulated-Annealing-Based Ising Machines
We propose a novel type of minor-embedding (ME) in simulated-annealing-based Ising machines. The Ising machines can solve combinatorial optimization problems. Many combinatorial optimization problems are mapped to find the ground (lowest-energy) state of
Tatsuhiko Shirai +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
HitIct:Chinese corpus for the evaluation of lossless compression algorithms
HitIct, a Chinese corpus for the evaluation of lossless compression algorithms based on ANSI code, was proposed.In accordance with the principle of application representativeness, Complementary principle and openness principle, a large number of ...
CHANG Wei-ling1 +3 more
doaj +2 more sources
Testing the cosmological principle with quasars
The cosmological principle posits that the universe is homogeneous and isotropic on the large scales. In history, the cosmological principle was confirmed by various cosmological observations from CMB to large scale structure.
Chen Shuangnan +7 more
doaj +1 more source
Full counting statistics approach to the quantum non-equilibrium Landauer bound
We develop the full counting statistics of dissipated heat to explore the relation with Landauer’s principle. Combining the two-time measurement protocol for the reconstruction of the statistics of heat with the minimal set of assumptions for Landauer’s ...
Giacomo Guarnieri +5 more
doaj +1 more source
Air conditioning is a load with thermal inertia, and short time control will not cause an obvious negative impact on user power consumption. Compared with the traditional mini-split-type air conditioner, it has the advantages of flexible control method ...
Meng Liu +3 more
doaj +1 more source
A Large Deviation Principle in Many-Body Quantum Dynamics. [PDF]
Kirkpatrick K, Rademacher S, Schlein B.
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

