Results 131 to 140 of about 8,481,699 (293)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Large deviation principles for countable Markov shifts

open access: yesTransactions of the American Mathematical Society, 2019
We establish the large deviation principle for a topological Markov shift over infinite alphabet which satisfies strong connectivity assumptions called “finite irreducibility” or “finite primitiveness”. More precisely, we assume the existence of a Gibbs state for a potential
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Large deviation principle at fixed time in Glauber evolutions Large deviation principle at fixed time in Glauber evolutions

open access: yes, 2020
: We consider the evolution of an asymptotically decoupled probability measure ν on Ising spin configurations under a Glauber dynamics. We prove that for any t > 0, ν t is asymptotically decoupled and hence satisfies a large deviation principle with ...
Frank Redig, Arnaud Le Ny
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Large Deviation Principle of Stochastic Evolution Equations with reflection [PDF]

open access: yes
In this paper, we establish a large deviation principle for stochastic evolution equations with reflection in an infinite dimensional ball.
Brzeźniak, Zdzisław   +2 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Accuracy of robotic computer-assisted implant surgery in clinical studies: a systematic review and meta-analysis

open access: yesBMC Oral Health
Objectives To analyze the accuracy of the robotic system in clinical studies and assess potential factors that might affect the accuracy of robotic implant placement.
Zixin Luo   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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