Results 101 to 110 of about 2,121,332 (279)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Web renewal counting processes and their applications in insurance

open access: yesJournal of Inequalities and Applications, 2018
This paper investigates a nonstandard renewal counting process with dependent inter-arrival times-web renewal process. Several limit properties, including the tail of the exponential moment which is a crucial condition in many situations, are obtained ...
Rong Li, Xiuchun Bi, Shuguang Zhang
doaj   +1 more source

Convexity and Large Deviations

open access: yesThe Annals of Probability, 1984
In a previous paper [ibid. 11, 158-167 (1983; Zbl 0503.60035), the author introduced a concept of ''dominating'' points to establish a nice representation formula and improved asymptotics for the probabilities of large deviations of random walks on \({\mathbb{R}}^ d\).
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Large Deviations for Mixtures

open access: yesElectronic Communications in Probability, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Minimum Description Length Codes Are Critical

open access: yesEntropy, 2018
In the Minimum Description Length (MDL) principle, learning from the data is equivalent to an optimal coding problem. We show that the codes that achieve optimal compression in MDL are critical in a very precise sense.
Ryan John Cubero   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

High-dimensional random landscapes: From typical to large deviations

open access: yesSciPost Physics Lecture Notes
We discuss tools and concepts that emerge when studying high-dimensional random landscapes, i.e., random functions on high-dimensional spaces. As an illustrative example, we consider an inference problem in two forms: low-rank matrix estimation (case 1 ...
Valentina Ros
doaj   +1 more source

Precise Large Deviations for Subexponential Distributions in a Multi Risk Model

open access: yesRisks, 2018
The precise large deviations asymptotics for the sums of independent identical random variables when the distribution of the summand belongs to the class S ∗ of heavy tailed distributions is studied.
Dimitrios G. Konstantinides
doaj   +1 more source

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