Results 121 to 130 of about 727,226 (339)

Precise Large Deviations for Subexponential Distributions in a Multi Risk Model

open access: yesRisks, 2018
The precise large deviations asymptotics for the sums of independent identical random variables when the distribution of the summand belongs to the class S ∗ of heavy tailed distributions is studied.
Dimitrios G. Konstantinides
doaj   +1 more source

Learning and Model Validation [PDF]

open access: yes
This paper studies the following problem. An agent takes actions based on a possibly misspecified model. The agent is 'large', in the sense that his actions influence the model he is trying to learn about.
Kenneth Kasa, In-Koo Cho
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

High-dimensional random landscapes: From typical to large deviations

open access: yesSciPost Physics Lecture Notes
We discuss tools and concepts that emerge when studying high-dimensional random landscapes, i.e., random functions on high-dimensional spaces. As an illustrative example, we consider an inference problem in two forms: low-rank matrix estimation (case 1 ...
Valentina Ros
doaj   +1 more source

Large deviations

open access: yes, 2016
The theory of large deviations deals with rates at which probabilities of certain events decay as a natural parameter in the problem varies. This book, which is based on a graduate course on large deviations at the Courant Institute, focuses on three ...
Varadhan, S R S   +1 more
core  

Large deviations formalism for multifractals

open access: yes, 1999
For a wide class of measures, the multifractal spectrum is shown to exist iff an appropriate large deviations principle holds, in which case the spectrum is directly obtained from the corresponding rate function. A large deviations tool, enabling the use
Gady Zohar, Zohar, Gady
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Large deviations in Coulomb gases: A mathematical perspective

open access: yesSciPost Physics Lecture Notes
These notes account for five ninety-minute lectures given by Mylène Maïda as part of the 2024 Summer School in Les Houches. This 4-week program was entitled Large deviations and applications.
Mylène Maïda, Antony Fahmy, Jan-Luka Fatras, Yilin Ye
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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