Results 91 to 100 of about 157,284 (291)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

Advanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed, Carl E. Eskildsen, Luca Panariello, André Shamsabadi, Christy J. Sadler, Edmund H. Wilkes, Federico Galvanin, Yuxi Cheng, Sara Carvalho, Srdjan Saso, Molly M. Stevens   +10 more
wiley   +1 more source

Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing

Advanced Science, EarlyView.
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo, Tianhao Yu, Yumin Dai, Seokkyoon Hong, Axel González Cornejo, Tristan Michael Long, Sang Mok Park, Pete S. Kollbaum, Edgar Bolívar‐Nieto, Young L. Kim, Dong Rip Kim, Chi Hwan Lee   +11 more
wiley   +1 more source

Nanocurvature‐Activated Dipolar Polarization in M–N4 Single‐Atom Sites for High‐Performance Electromagnetic Wave Absorption

Advanced Science, EarlyView.
Increasing nanocurvature effectively enriches the local electron density of the M–N4 motif, which facilitates electron transfer from the metal center to nitrogen atoms. This electronic behavior intensifies the localization and asymmetric distribution of charge, thereby significantly amplifying the dipole moment and polarizability.
Daohu Sheng, Siyao Cheng, Mengmeng Zhang, Jinglei Zhang, Xufei Zhu, Weijin Li, Bo Zhang, Aming Xie   +7 more
wiley   +1 more source

Convergent Valorization via Scalable C═N Bond Electrosynthesis Through Metal‐Dopant Interfacial Engineering in a Flow Electrolyzer

Angewandte Chemie, EarlyView.
This study establishes an innovative approach to synthesize organonitrogens featuring C═N bonds efficiently using non‐precious metal‐doped MoS2 in a flow electrolyzer. Fe dopant significantly enhances Faradaic efficiency and yield rate, achieving over 81% and 2630 mmol h−1 g−1 for formaldoxime production. This platform upcycles pollutants into valuable
Ruijie Yi, Jiu Chen, Xiaoyong Mo, Tian Zeng, Jingtao Zhou, Fulai Liu, Shu‐Chih Haw, Yong Chen, Ruosong Li, Edmund C. M. Tse   +9 more
wiley   +2 more sources

Numerical analysis of lifted hydrogen flame

MATEC Web of Conferences, 2018
A numerical analysis of a turbulent lifted H2/N2 flame is presented. As combustion mechanisms, a large spectrum is considered including single-step and two-step, as well as detailed mechanisms.
Iqbal Sohail, Pfeiffelmann Björn, Benim Ali Cemal, Joos Franz   +3 more
doaj   +1 more source

What Controls the Water Vapor Isotopic Composition Near the Surface of Tropical Oceans? Results From an Analytical Model Constrained by Large‐Eddy Simulations

Journal of Advances in Modeling Earth Systems, 2020
The goal of this study is to understand the mechanisms controlling the isotopic composition of the water vapor near the surface of tropical oceans, at the scale of about a hundred kilometers and a month. In the tropics, it has long been observed that the
Camille Risi, Caroline Muller, Peter Blossey   +2 more
doaj   +1 more source

Large-eddy simulation for flow and dispersion in urban streets

, 2009
Large-eddy simulations (LES) with our recently developed inflow approach (Xie &Castro, 2008a) have been used for flow and dispersion within a genuine city area -the DAPPLE site, located at the intersection of Marylebone Rd and Gloucester Plin Central
Castro, Ian P., Xie, Zheng-Tong
core   +1 more source

Liquid Metals in Radio Frequency Applications: A Review of Physics, Manufacturing, and Emerging Technologies

Advanced Electronic Materials, EarlyView.
This paper reviews the physics of liquid metals in RF devices, including the influence of mechanical strain on resonance as well as fabrication methods and strategies for designing tunable and strain‐tolerant inductors, capacitors, and antennas.
Md Saifur Rahman, William J. Scheideler
wiley   +1 more source

Large eddy simulation of auto-igniting methanol/n-dodecane blend spray flames

Fuel Processing Technology
The study investigates the auto-ignition characteristics of methanol/n-dodecane fuel blends at varying blend ratios and ambient temperatures using large eddy simulation (LES) in OpenFOAM with the Engine Combustion Network (ECN) Spray-D injector.
Bishal Shrestha, Fatimoh Balogun, Kevin Wan, Junghwa Yi, Huaying Wang-Alho, Shervin Karimkashi, Katriina Sirvio, Julien Manin, Maciej Mikulski, Jari Hyvönen, Ossi Kaario   +10 more
doaj   +1 more source