Results 91 to 100 of about 26,008 (308)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Large-eddy simulation of flows over random urban-like obstacles

open access: yes, 2008
Further to our previous large-eddy simulation (LES) of flow over a staggered array of uniform cubes, a simulation of flow over random urban-like obstacles is presented. To gain a deeper insight into the effects of randomness in the obstacle topology, the
Coceal, Omduth   +2 more
core   +1 more source

Large-Eddy simulation of pulsatile blood flow [PDF]

open access: yes, 2009
Large-Eddy simulation (LES) is performed to study pulsatile blood flow through a 3D model of arterial stenosis. The model is chosen as a simple channel with a biological type stenosis formed on the top wall.
Molla, M.M., Roditi, G., Paul, M.C.
core   +1 more source

Eulerian – Eulerian Large Eddy Simulations Applied to Non-Reactive Transient Diesel Sprays

open access: yesOil & Gas Science and Technology, 2013
The aim of this study is to perform and analyze LES (Large Eddy Simulations) simulations of transient Diesel sprays in a high-pressure and high-temperature vessel. In order to be representative of real Diesel injection strategies, two
Robert Anthony   +3 more
doaj   +1 more source

Large-Eddy Simulations of Shear Flows

open access: yesJournal of Engineering Mathematics, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lesieur, Marcel   +4 more
openaire   +2 more sources

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

open access: yesAdvanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar   +10 more
wiley   +1 more source

Simulations aux grandes échelles : application au jet transverse [PDF]

open access: yes, 2005
Depuis plusieurs années, l'industrie des turbines à gaz place au cœur de sa stratégie de recherche les enjeux à la fois environnementaux et économiques tels que : la diminution des polluants et des nuisances sonores et la réduction de consommation du ...
Prière, Céline
core   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

Efficient generation of inflow conditions for large-eddy simulation of street-scale flows

open access: yes, 2008
Using a numerical weather forecasting code to provide the dynamic largescale inlet boundary conditions for the computation of small-scale urban canopy flows requires a continuous specification of appropriate inlet turbulence.
Xie, Zheng-Tong, Castro, Ian P.
core   +1 more source

Surface‐Spin‐Induced Magnetic Loss Enhancement in Ultralight Electromagnetic Absorbers

open access: yesAdvanced Science, EarlyView.
Fe3O4 nanoparticles with different hollow rates were synthesized to demonstrate the key role of surface moment in magnetic loss process. Using the same volume filling ratio, the 54.1% hollow Fe3O4 absorber represents about 20% enhancement in the imaginary part (μ'') than solid particles due to the coexisting magnetic resonance of inside and outside ...
Ruimin Ren   +5 more
wiley   +1 more source

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