Results 201 to 210 of about 257,227 (292)

Multivariate Trajectories of Eating Disorder Symptoms and Weight Status in 10‐ to 17‐Year‐Old Children and Adolescents

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) often emerge in adolescence, but developmental trajectories across different core features remain largely unclear. Method The prospective, community‐based study included N = 898 participants aged 9.5–17.5 years (47.6% female, age 11.8 ± 1.4 years) with annual follow‐up over 2–6 (3.4 ± 1.2) years.
Anja Hilbert   +5 more
wiley   +1 more source

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

open access: yesEpilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin   +7 more
wiley   +1 more source

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan   +20 more
wiley   +1 more source

Effects of perinatal variables on echocardiographic assessments of left ventricular dimensions in infants born large for gestational age: a prospective cohort analysis. [PDF]

open access: yesItal J Pediatr
Amarah A   +11 more
europepmc   +1 more source

Long‐term safety of early discontinuation of antiseizure medication after resolution of acute provoked neonatal seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective To assess long‐term safety of antiseizure medication (ASM) discontinuation after resolution of acute provoked neonatal seizures and prior to hospital discharge. Methods Prospective, observational, comparative effectiveness cohort study of neonates with acute provoked seizures born from July 2015 to March 2018, and followed until ...
Hannah C. Glass   +16 more
wiley   +1 more source

Geospatial Determinants of Maternal Overweight, Gestational Diabetes and Large for Gestational Age Birthweight in Melbourne During and After COVID-19 Lockdowns. [PDF]

open access: yesAust N Z J Obstet Gynaecol
Marzan MB   +12 more
europepmc   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

open access: yesEpilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn   +7 more
wiley   +1 more source

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