Results 71 to 80 of about 86,999,459 (294)
Diabetology & Metabolic Syndrome, 2019 Background Both obesity and gestational diabetes (GDM) are associated with adverse outcomes. Diet during pregnancy impacts weight gain and fetal growth. Therefore, we aimed to explore non-pharmacological treatment success depending on pre-pregnancy body ...
Ana Munda +5 more
doaj +1 more source
TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains
Advanced Science, EarlyView.Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang +14 more
wiley +1 more source
Large‐for‐gestational age and stillbirth: is there a role for antenatal testing? [PDF]
Ultrasound in Obstetrics & Gynecology, 2019 ABSTRACTObjectiveTo investigate the association between large‐for‐gestational‐age (LGA) pregnancy and stillbirth to determine if the LGA fetus may benefit from antenatal testing with non‐stress test or biophysical profile.MethodsThis was a retrospective cohort study of singleton pregnancies that were ongoing at 24 weeks' gestation and that had ...
E. B. Carter +5 more
openaire +2 more sources
SAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source
BMC Pregnancy and ChildbirthBackground Restricted gestational weight gain (GWG) following lifestyle interventions for gestational diabetes mellitus (GDM) has been observed in clinical trials but not been explicitly confirmed in real-world clinical settings.
Juan Li, Chuanzi Yang, Kuanrong Li
doaj +1 more source
Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight
, 2019 ObjectiveNonalcoholic fatty liver disease (NAFLD) is a well-recognized hepatic manifestation of metabolic disease in adults and has been associated with the development of gestational diabetes (GDM).
Won Kim +31 more
core +1 more source
, 2022 Effect of maternal vitamin D3 supplementation on small-for-gestational-age live births and secondary birth and infant outcomes.
Ning Zhang (23771) +9 more
core +1 more source
Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli
Advanced Science, EarlyView.Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma +18 more
wiley +1 more source
Accuracy of circulating adiponectin for predicting gestational diabetes : a systematic review and meta-analysis [PDF]
, 2016 Aims/hypothesis Universal screening for gestational diabetes mellitus (GDM) has not been implemented, and this has had substantial clinical implications. Biomarker-directed targeted screening might be feasible.
Kelsey, Tom +21 more
core +1 more source
Advanced Science, EarlyView.Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang +9 more
wiley +1 more source