Results 71 to 80 of about 257,227 (292)

Plasma Glycated CD59 Predicts Early Gestational Diabetes and Large for Gestational Age Newborns

The Journal of Clinical Endocrinology & Metabolism, 2020
AbstractContextGestational diabetes mellitus (GDM) diagnosed in early pregnancy is a health care challenge because it increases the risk of adverse outcomes. Plasma-glycated CD59 (pGCD59) is an emerging biomarker for diabetes and GDM. The aim of this study was to assess the performance of pGCD59 as a biomarker of early GDM and its association with ...
DongDong Ma, Miguel Angel Luque-Fernandez, Delia Bogdanet, Gernot Desoye, Fidelma Dunne, Jose A Halperin   +5 more
openaire   +3 more sources

A retrospective segmentation analysis of placental volume by magnetic resonance imaging from first trimester to term gestation [PDF]

, 2018
Background Abnormalities of the placenta affect 5–7% of pregnancies. Because disturbances in fetal growth are often preceded by dysfunction of the placenta or attenuation of its normal expansion, placental health warrants careful surveillance. There are
Brown, Brandon P., León, Rachel L., Li, Kevin T.   +2 more
core   +1 more source

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J.T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Pre-eclampsia is associated with a twofold increase in diabetes : a systematic review and meta-analysis [PDF]

, 2016
CSK and RH are funded by National Institute for Health Research Academic Clinical Fellowships.
Babu, Aswin, Chew-Graham, Carolyn A, Fryer, Anthony A., Haththotuwa, Randula, Kotronias, Rafail A, Kwok, Chun Shing, Mamas, Mamas A, Myint, Phyo K., Wu, Pensee   +8 more
core   +3 more sources

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Macrosomia and large for gestational age in Asia

Journal of Obstetrics and Gynaecology Research, 2021
Macrosomia, usually defined as infant birth weight of >= 4000 g, does not consider gestational age, sex, or country/region-specific differences in mean birth weight and maternal body weight. This issue is particularly relevant for Asia, where 60% of the world's population lives, due to variations in maternal size and birth weights across populations.
Harvey, Louise, van Elburg, Ruurd, van der Beek, Eline M.   +2 more
openaire   +1 more source

Sonographic cervical volumetry in higher order multiple gestation [PDF]

, 2001
Objective:The aim of this study of multifetal pregnancies was the comparison of three-dimensional (3D) volumetry of the cervix, conventional sonographic cervical length measurement and clinical assessment.
Fuchshuber, Susanne, Heer, Ivo, Hepp, Hermann, Hillemanns, Peter, Janssen, Udo, Strauss, Alexander   +5 more
core   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Association between pre-pregnancy body weight and dietary pattern with large-for-gestational-age infants in gestational diabetes

Diabetology & Metabolic Syndrome, 2019
Background Both obesity and gestational diabetes (GDM) are associated with adverse outcomes. Diet during pregnancy impacts weight gain and fetal growth. Therefore, we aimed to explore non-pharmacological treatment success depending on pre-pregnancy body ...
Ana Munda, Marjanca Starčič Erjavec, Katja Molan, Jerneja Ambrožič Avguštin, Darja Žgur-Bertok, Draženka Pongrac Barlovič   +5 more
doaj   +1 more source

LARGE-FOR-GESTATIONAL-AGE NEWBORNS: CAUSES AND CONSEQUENCES

Slovenska pediatrija, revija pediatrov Slovenije in specialistov šolske ter visokošolske medicine Slovenije, 2020
Large-for-gestational-age newborns are defined as having a birth weight and/or birth length above the 90th percentile for gestational age and sex. Through epigenetic mechanisms, the suboptimal intrauterine environment influences the phenotypic changes in the metabolic and endocrine pathways of the foetus.
Mojca Železnik, Aneta Soltirovska Šalamon   +1 more
openaire   +2 more sources