Results 31 to 40 of about 3,038,337 (264)

Improving Language Modelling with Noise-contrastive estimation

, 2017
Neural language models do not scale well when the vocabulary is large. Noise-contrastive estimation (NCE) is a sampling-based method that allows for fast learning with large vocabularies.
Grzes, Marek, Liza, Farhana Ferdousi
core   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek, Lori Wiener, Stephanie Veldhuijzen van Zanten, Donna Johnston, Fyeza Hasan, Adam Rapoport, Nathasha Datoo, Kimberley Widger, Sumit Gupta, Karen Fergus, Anthony K. C. Chan, Alisha Kassam, Emily McCullogh, Dave Lysecki   +13 more
wiley   +1 more source

DB-GPT: Large Language Model Meets Database

Data Science and Engineering
Large language models (LLMs) have shown superior performance in various areas. And LLMs have the potential to revolutionize data management by serving as the "brain" of next-generation database systems.
Xuanhe Zhou, Zhaoyan Sun, Guoliang Li
doaj   +1 more source

Enhancing Personalized Fitness: Integrating Large Language Model [PDF]

EPJ Web of Conferences
This paper explores the integration of Large Language Models (LLMs) into workout planning and personal training to meet the growing demand for personalized fitness solutions.
Pardhi Praful R., Wagh Saurabh, Sharma Gaurav, Goyal Abhash, Pawar Pavan   +4 more
doaj   +1 more source

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

Evaluation of large language models under different training background in Chinese medical examination: a comparative study

Frontiers in Artificial Intelligence
BackgroundRecently, Large Language Models have shown impressive potential in medical services. However, the aforementioned research primarily discusses the performance of LLMs developed in English within English-speaking medical contexts, ignoring the ...
Siwen Zhang, Qi Chu, Yujun Li, Jialu Liu, Jiayi Wang, Chi Yan, Wenxi Liu, Yizhen Wang, Chengcheng Zhao, Xinyue Zhang, Yuwen Chen   +10 more
doaj   +1 more source

Autoformalization with Large Language Models

, 2022
Autoformalization is the process of automatically translating from natural language mathematics to formal specifications and proofs. A successful autoformalization system could advance the fields of formal verification, program synthesis, and artificial intelligence.
Wu, Yuhuai, Jiang, Qiaochu, Li, Wenda, Rabe, Markus, Staats, Charles, Jamnik, Mateja, Szegedy, Christian   +6 more
openaire   +3 more sources

Segatron: Segment-Aware Transformer for Language Modeling and Understanding

, 2020
Transformers are powerful for sequence modeling. Nearly all state-of-the-art language models and pre-trained language models are based on the Transformer architecture. However, it distinguishes sequential tokens only with the token position index.
Bai, He, Gao, Wen, Li, Ming, Lin, Jimmy, Shi, Peng, Tan, Luchen, Xie, Yuqing, Xiong, Kun   +7 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source