Results 71 to 80 of about 22,635,901 (285)

Knowledge-guided large language model for material science

Review of Materials Research
With ChatGPT starting a storm of transformative applications worldwide, the advent of large language models (LLMs) has revolutionized the paradigm of scientific research, shifting from data-driven methods to AI-driven science.
Guanjie Wang, Jingjing Hu, Jian Zhou, Sen Liu, Qingjiang Li, Zhimei Sun   +5 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Large Language Models in Healthcare

CoRR
Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration requires rigorous development, adaptation, and evaluation strategies tailored to clinical needs.
Mohammed Ali Al-Garadi, Tushar Mungle, Abdulaziz Ahmed, Abeed Sarker, Zhuqi Miao, Michael E. Matheny   +5 more
openaire   +2 more sources

Comparison of Large Language Model with Aphasia

Advanced Science
Large language models (LLMs) respond fluently but often inaccurately, which resembles aphasia in humans. Does this behavioral similarity indicate any resemblance in internal information processing between LLMs and aphasic humans?
Takamitsu Watanabe, Katsuma Inoue, Yasuo Kuniyoshi, Kohei Nakajima, Kazuyuki Aihara   +4 more
doaj   +1 more source

FlowLLM: Large language model driven flow visualization

Visual Informatics
Flow visualization is an essential tool for domain experts to understand and analyze flow fields intuitively. In the past decades, various interactive techniques were developed to customize flow visualization for exploration.
Zilin Li, Weihan Zhang, Jun Tao
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Modelling language using large language models

Philosophical Studies
Abstract This paper argues that large language models have a valuable scientific role to play in serving as scientific models of public languages. Linguistic study should not only be concerned with the cognitive processes behind linguistic competence, but also with language understood as an external, social entity.
openaire   +2 more sources

Idiosyncrasies in Large Language Models

CoRR
Published in ICML 2025.
Mingjie Sun, Yida Yin, Zhiqiu Xu, J. Zico Kolter, Zhuang Liu 0003   +4 more
openaire   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source