Results 51 to 60 of about 2,402,901 (306)

Process Modeling with Large Language Models

open access: yes
In the realm of Business Process Management (BPM), process modeling plays a crucial role in translating complex process dynamics into comprehensible visual representations, facilitating the understanding, analysis, improvement, and automation of organizational processes.
Humam Kourani   +3 more
openaire   +2 more sources

Compositional Morphology for Word Representations and Language Modelling [PDF]

open access: yes, 2014
This paper presents a scalable method for integrating compositional morphological representations into a vector-based probabilistic language model. Our approach is evaluated in the context of log-bilinear language models, rendered suitably efficient for ...
Blunsom, Phil, Botha, Jan A.
core   +1 more source

Towards Automatic Generation of Shareable Synthetic Clinical Notes Using Neural Language Models

open access: yes, 2019
Large-scale clinical data is invaluable to driving many computational scientific advances today. However, understandable concerns regarding patient privacy hinder the open dissemination of such data and give rise to suboptimal siloed research.
Melamud, Oren, Shivade, Chaitanya
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Improving Language Modelling with Noise-contrastive estimation

open access: yes, 2017
Neural language models do not scale well when the vocabulary is large. Noise-contrastive estimation (NCE) is a sampling-based method that allows for fast learning with large vocabularies.
Grzes, Marek, Liza, Farhana Ferdousi
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Talking about Large Language Models

open access: yesCommunications of the ACM
Interacting with a contemporary LLM-based conversational agent can create an illusion of being in the presence of a thinking creature. Yet, in their very nature, such systems are fundamentally not like us.
openaire   +4 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Uncertainty quantification by large language models

open access: yesMachine Learning with Applications
As reasoning capabilities of large language models (LLMs) continue to advance, they are being integrated into increasingly complex scientific workflows, with the goal of developing agents capable of generating evidence-based explanations and testing ...
Dorianis M. Perez   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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