Results 61 to 70 of about 2,402,901 (306)

Ensemble Large Language Models: A Survey

Information
Large language models (LLMs) have transformed the field of natural language processing (NLP), achieving state-of-the-art performance in tasks such as translation, summarization, and reasoning.
Ibomoiye Domor Mienye, Theo G. Swart
doaj   +1 more source

Large Language Models Are Biased Because They Are Large Language Models

Computational Linguistics
Abstract This position paper’s primary goal is to provoke thoughtful discussion about the relationship between bias and fundamental properties of large language models (LLMs). I do this by seeking to convince the reader that harmful biases are an inevitable consequence arising from the design of any large language model as LLMs are ...
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Large language models in critical care

Journal of Intensive Medicine
The advent of chat generative pre-trained transformer (ChatGPT) and large language models (LLMs) has revolutionized natural language processing (NLP).
Laurens A. Biesheuvel, Jessica D. Workum, Merijn Reuland, Michel E. van Genderen, Patrick Thoral, Dave Dongelmans, Paul Elbers   +6 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Industrial applications of large language models

Scientific Reports
Large language models (LLMs) are artificial intelligence (AI) based computational models designed to understand and generate human like text. With billions of training parameters, LLMs excel in identifying intricate language patterns, enabling remarkable
Mubashar Raza, Zarmina Jahangir, Muhammad Bilal Riaz, Muhammad Jasim Saeed, Muhammad Awais Sattar   +4 more
doaj   +1 more source

Large Language Models: А Socio-Philosophical Essay

Галактика медиа: журнал медиа исследований
Neural networks have filled the information space. On the one hand, this indicates the scientific and technological movement of contemporary society (perhaps, AGI is already waiting for us outside the door). On the other hand, in everyday discourse there
Regina V. Penner
doaj   +1 more source

Confronting LLMs with Traditional ML: Rethinking the Fairness of Large Language Models in Tabular Classifications [PDF]

, 2023
Yanchen Liu, Srishti Gautam, Jiaqi Ma, Himabindu Lakkaraju   +3 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source