Results 201 to 210 of about 13,620,505 (264)

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

Computational Analysis of the Vibrational Response of Lunar Regolith Made of Nonspherical Grains

open access: yesInternational Journal for Numerical and Analytical Methods in Geomechanics, EarlyView.
ABSTRACT Vibration‐based systems have shown that appropriately oriented and tuned mechanical oscillations can disrupt regolith interlocking and promote flow. Building on this evidence, the present study investigates vibration‐controlled granular discharge as a potential ISRU (In Situ Resource Utilization) strategy, with the aim of supporting ...
Lewis Traquair   +4 more
wiley   +1 more source

Integrating Grain to Ground Motion Data for Critical Rock Bridge and Slope Failure Analysis

open access: yesInternational Journal for Numerical and Analytical Methods in Geomechanics, EarlyView.
ABSTRACT Rock masses can fail catastrophically with little warning, yet their stability depends on hidden internal connections that channel forces and localise damage. Among these, rock bridges–a “known unknown” in slope mechanics–lock fractured rock and control how failure unfolds, but their concealed geometry and uncertain strength obscure where and ...
Antoinette Tordesillas   +5 more
wiley   +1 more source

Aiouea riedeliana comb. nov. (Lauraceae) from Brazil, with an amended description and provisional extinction threat assessment

open access: yesNordic Journal of Botany, EarlyView.
Aiouea riedeliana (Kosterm.) P.L.R.Moraes and Brotto is the new combination for Cinnamomum riedelianum Kosterm., whose type‐bringing synonym is Persea riedelii Meisn. The placement of this taxon in Aiouea is presented, justified, and illustrated here, disagreeing with its previous classification in Ocotea, as Ocotea riedeliana (Kosterm.) Kottaim., then
Pedro Luís Rodrigues de Moraes   +2 more
wiley   +1 more source

From mainland to islands: the evolution of resistance and tolerance to herbivory in long‐lived oaks

open access: yesOikos, EarlyView.
Island biogeography theory predicts that island plants should exhibit reduced defences compared with their mainland relatives due to relaxed herbivory pressure. However, growing empirical evidence challenges this prediction, revealing substantial variation among systems, plant lineages and defence types.
Irene Virseda   +16 more
wiley   +1 more source

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