Results 51 to 60 of about 14,738,138 (292)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Black Phosphorus Q-Switched Large-Mode-Area Tm-Doped Fiber Laser
International Journal of Optics, 2018 We report on a passively Q-switched fiber laser with black phosphorus as saturable absorber. By employing the sol-gel fabricated large-mode-area Tm-doped fiber as gain medium, a high-energy Q-switched fiber laser has been demonstrated which delivers the ...
Yan Ren +9 more
doaj +1 more source
Advanced fibre designs for high power laser beam delivery and generation [PDF]
, 2009 Microstructured optical fiber (MOF) technology provides a powerful means to develop fibers with unique and enabling properties with potential uses spanning a very wide range of applications.
Hayes, John +11 more
core +2 more sources
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
, 2011 We investigate efficient broadband infrared supercontinuum generation in meter-length single-mode small-core tellurite holey fiber. The fiber is pumped by 1.06µm picosecond pulses in the normal dispersion region.
Shi, Jindan +8 more
core +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Bendable large-mode-area fiber with a non-circular core [PDF]
Applied Optics, 2018 We investigate mode-area-scaling and bending performances of a Yb-doped large-mode-area fiber with an elongated non-circular core. Such fiber can be bent in the plane of its short axis to suppress bending effects, such as mode area reduction and mode profile distortion.
Junhua Ji +6 more
openaire +5 more sources
Multi-kilowatt single-mode ytterbium-doped large-core fiber laser
, 2009 We have demonstrated a highly efficient cladding-pumped ytterbium-doped fiber laser, generating >2.1 kW of continuous-wave output power at 1.1 µm with 74% slope efficiency with respect to launched pump power.
Chung, Seung-Hwan +5 more
core +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Narrow Linewidth 49 W All Fiber Linearly Polarized Picosecond Laser Operating at 1016 nm
IEEE Photonics Journal, 2022 An all fiber linearly polarized narrow linewidth pulsed fiber laser operating at 1016 nm is demonstrated in a master oscillator power amplification (MOPA) configuration.
Chao Zhang +3 more
doaj +1 more source