Results 81 to 90 of about 4,498,304 (271)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Cross section, final spin and zoom-whirl behavior in high-energy black hole collisions
We study the collision of two highly boosted equal mass, nonrotating black holes with generic impact parameter. We find such systems to exhibit zoom-whirl behavior when fine tuning the impact parameter.
E. Witten +9 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Darwin Meets Einstein: LISA Data Analysis Using Genetic Algorithms
This work presents the first application of the method of Genetic Algorithms (GAs) to data analysis for the Laser Interferometer Space Antenna (LISA). In the low frequency regime of the LISA band there are expected to be tens of thousands galactic binary
C. Darwin +5 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Error Analysis and Parameter Recommendations for Randomness Test Under Large Sample Conditions [PDF]
In the field of information security,randomness tests play a crucial role in ensuring the security of cryptographic systems.The stability and reliability of these tests directly impact the overall security of cryptographic systems,making error issues ...
SUN Yueyue, FAN Limin
doaj +1 more source
Large Scale Inhomogeneities from the QCD Phase Transition
We examine the first-order cosmological QCD phase transition for a large class of parameter values, previously considered unlikely. We find that the hadron bubbles can nucleate at very large distance scales, they can grow as detonations as well as ...
A. Guth +24 more
core +2 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On parameter identification for large space structures [PDF]
The design of a controller for large space structures (LSS) based on the LQG theory requires the knowledge of the LSS parameters. Since apriori knowledge of the parameters is usually not reliable, the parameters must be identified prior to the controller
Goglia, G. L., Joshi, S. M.
core +1 more source
Three-Loop Electroweak Correction to the Rho Parameter in the Large Higgs Mass Limit
We present an analytical calculation of the leading three-loop radiative correction to the rho-parameter in the Standard Model in the large Higgs mass limit.
Akhoury +30 more
core +2 more sources

