Results 71 to 80 of about 805,278 (315)

Population structure and comparative genome hybridization of European flor yeast reveal a unique group of Saccharomyces cerevisiae strains with few gene duplications in their genome. [PDF]

PLoS ONE, 2014
Wine biological aging is a wine making process used to produce specific beverages in several countries in Europe, including Spain, Italy, France, and Hungary. This process involves the formation of a velum at the surface of the wine. Here, we present the
Jean-Luc Legras, Claude Erny, Claudine Charpentier   +2 more
doaj   +1 more source

Experimental Validation of Finite Element Analysis of Human Vertebral Collapse Under Large Compressive Strains

, 2014
Osteoporosis-related vertebral fractures represent a major health problem in elderly populations. Such fractures can often only be diagnosed after a substantial deformation history of the vertebral body.
Clouthier, Allison L., Zysset, Philippe K., Hosseini, Hadi S.   +2 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The role of finite strain kinematics in the natural fibre reinforcement of peat and other soft organic soils

Scientific Reports
Peat is a highly organic and fibrous soil that often presents significant challenges in geotechnical engineering due to its unconventional high compressibility, shearing resistance and anisotropy.
Luis J. Parra-Gómez, Cristina Jommi, Stefano Muraro   +2 more
doaj   +1 more source

Stress State of Modular Blocks with Large Door Openings

Buildings
Modular construction is a modern and efficient type of construction that has gained wide recognition in the construction industry. Limited research has been conducted on how large door openings affect the stress state of modular blocks. The present study
Ilia Teshev, Aliy Bespayev, Murat Tamov, Zauresh Zhambakina, Ulan Altigenov, Timur Zhussupov, Aigerim Tolegenova   +6 more
doaj   +1 more source

MOLECULAR PHYLOGENETIC ANALYSIS OF MONASCUS FUNGI BASED ON INTERNAL TRANSCRIBED SPACER REGION

Biotropia: The Southeast Asian Journal of Tropical Biology, 2011
A molecular analysis of internal transcribed spacer region has been carried out to reveal the relationship among 16 strains of Monascus spp. A primer set comprised primer ITS1 and ITS4 was used to amplify this region in which they were cloned and ...
N SUHARNA, Y. KIKUCHI, T. FUKATSU
doaj   +1 more source

Impact of ecophysiological factors on biocontrol of aflatoxin contamination of maize by atoxigenic aspergillus flavus strains [PDF]

, 2013
This study has (a) evaluated the biodiversity in toxigenic mycobiota associated with maize from subsistence farmers’ stores in five climatic regions of Lesotho in two seasons, (b) compared the effect of ecophysiological factors on interactions between ...
Mohale, Sejakhosi Alexis
core  

Volatile compound fingerprinting of mixed-culture fermentations. [PDF]

, 2011
Item does not contain fulltextWith the advent of the -omics era, classical technology platforms, such as hyphenated mass spectrometry, are currently undergoing a transformation toward high-throughput application.
Hylckama, J., van, Sieuwerts, S., Molenaar, D, Arjen Lommen, Bayjanov, J.R., Molenaar, D., van Hylckama, J., Molenaar, D.; id_orcid, Janssen, P.W.M., Bok, F.A. de, van Hylckama Vlieg, J.E.T., Patrick W. M. Janssen, Douwe Molenaar, Jumamurat R. Bayjanov, Bayjanov, J., Johan E. T. van Hylckama Vlieg, Sander Sieuwerts, Hylckama Vlieg, J.E.T. van, de Bok, F.A.M., Lommen, A., Bok, F.A.M., de, Bok, F.A.M. de, Janssen, P.W., Frank A. M. de Bok, Hylckama Vlieg, J.E. van   +24 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source