Tenecteplase Averting Mechanical Thrombectomy in Emergent Large Vessel Occlusion
Introduction: Tenecteplase has recently been studied as an alternative thrombolytic agent in acute stroke, with a possible superior effect in achieving reperfusion of large intracranial vessels. Case Report: A 90-year-old female patient was admitted to our stroke unit because of ...
Psychogios, K. +6 more
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The future of ischemic stroke: flow from prehospital neuroprotection to definitive reperfusion. [PDF]
Recent advances in ischemic stroke enable a seamless transition of the patient flow from the prehospital setting to definitive reperfusion, without the arbitrary separation of therapeutic phases of ischemia based on time alone.
Ip, Hing Lung, Liebeskind, David S
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Geometrical Designs in Volumetric Bioprinting to Study Cellular Behaviors in Engineered Constructs
Curvature and spatial confinement guide cell behavior in volumetrically printed 3D constructs. Endothelial cells align and spread along specific geometries, while metastatic osteosarcoma cells proliferate independently of structural cues. Label‐free holographic microscopy captures real‐time, long‐term cell–material interactions, highlighting Gel‐PEG's ...
Julia Simińska‐Stanny +3 more
wiley +1 more source
Association between time to reperfusion and outcome is primarily driven by the time from imaging to reperfusion [PDF]
Background and Purpose A progressive decline in the odds of favorable outcome as time to reperfusion increases is well known. However, the impact of specific workflow intervals is not clear.; Methods We studied the mechanical thrombectomy group (n=103 ...
Cerda, Neus +8 more
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Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
The 'Sphere': A Dedicated Bifurcation Aneurysm Flow-Diverter Device. [PDF]
We present flow-based results from the early stage design cycle, based on computational modeling, of a prototype flow-diverter device, known as the 'Sphere', intended to treat bifurcation aneurysms of the cerebral vasculature.
Cornhill, JF +4 more
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Cost-utility analysis: Mechanical thrombectomy plus thrombolysis in ischemic stroke due to large vessel occlusion in the public sector in Chile [PDF]
Rony Lenz-Alcayaga +3 more
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Smart Catheters for Diagnosis, Monitoring, and Therapy
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman +12 more
wiley +1 more source
Prehospital Scales for Large Vessel Occlusion [PDF]
See related article, p 290 . The strong evidence for benefits of rapid thrombectomy in patients with acute ischemic stroke (AIS) is challenging prehospital systems around the world. Although high-tech endovascular treatment (EVT) works only for a minority of patients, healthcare systems cannot afford to miss suitable candidates anymore. Recent figures
openaire +2 more sources
Vascular dementia: Current concepts and nomenclature harmonization. [PDF]
Several types of cerebrovascular lesions are associated with cognitive decline, but the role of each type in dementia manifestation has yet to be determined.
Grinberg, Lea Tenenholz
core

