Results 241 to 250 of about 333,893 (395)

Back Again to the Future: A New Era for Cerebroprotection

open access: yesAnnals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh   +4 more
wiley   +1 more source

Initial multicenter experience with the Raptor aspiration catheter for treating large vessel occlusion ischemic stroke. [PDF]

open access: yesInterv Neuroradiol
Venegas A   +8 more
europepmc   +1 more source

Thrombectomy versus Medical Management for Pediatric Acute Ischemic Stroke Due to Isolated M2 Occlusion: A Multicenter Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective Endovascular thrombectomy (EVT) is increasingly used for pediatric large vessel occlusion (LVO) stroke, however, its role in isolated M2 occlusions remains underexplored. This study compared clinical outcomes in children with isolated M2 occlusion treated with EVT versus best medical therapy (BMT). Methods This multicenter cohort study pooled
Peter B. Sporns   +24 more
wiley   +1 more source

Impact of stress hyperglycemia mediating tissue-level collaterals on futile recanalization in large vessel occlusion patients. [PDF]

open access: yesFront Endocrinol (Lausanne)
Li X   +8 more
europepmc   +1 more source

Intracerebral arterial blood pressure in the vasculature distal to large vessel occlusions in patients with ischemic stroke: correlation with clinical and imaging parameters [PDF]

open access: hybrid
Moritz Umhau   +9 more
openalex   +1 more source

Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy

open access: yesAnnals of Neurology, EarlyView.
Objective The first‐pass effect (FPE), defined as excellent reperfusion after a single attempt, is associated with improved outcomes in large vessel occlusion stroke. We evaluated whether intravenous tenecteplase (TNK) compared with alteplase (TPA) increases the likelihood of FPE in basilar artery occlusion (BAO).
Dylan N. Wolman   +38 more
wiley   +1 more source

Effect of Perforator Territory Infarction on Functional Outcome in Patients With Large Vessel Occlusion. [PDF]

open access: yesStroke
Sadigh Y   +11 more
europepmc   +1 more source

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