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2016
Select patients who are not eligible for IV tPA, or who do not recanalize with IV thrombolysis alone, may be treated with acute endovascular therapies within a 6-hour window. Mechanical thrombectomy, with or without intra-arterial tPA, has recently been shown to be effective in treating acute ischemic stroke caused by large vessel occlusion.
Ji Y. Chong, Michael P. Lerario
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Select patients who are not eligible for IV tPA, or who do not recanalize with IV thrombolysis alone, may be treated with acute endovascular therapies within a 6-hour window. Mechanical thrombectomy, with or without intra-arterial tPA, has recently been shown to be effective in treating acute ischemic stroke caused by large vessel occlusion.
Ji Y. Chong, Michael P. Lerario
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Large Cerebral Vessel Occlusive Disease in Lyme Neuroborreliosis
Neuropediatrics, 2002We report on a 12-year-old, previously healthy girl with an acute hemiparesis as the predominant clinical manifestation of Lyme neuroborreliosis (LNB). The diagnosis of LNB was based on cerebrospinal fluid (CSF) studies, laboratory findings and the clinical course whereas the patient's history and the lack of characteristic skin lesions obscured the ...
R, Klingebiel +4 more
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Characterizing coma in large vessel occlusion stroke
Journal of NeurologyComa is an unresponsive state of disordered consciousness characterized by impaired arousal and awareness. The epidemiology and pathophysiology of coma in ischemic stroke has been underexplored. We sought to characterize the incidence and clinical features of coma as a presentation of large vessel occlusion (LVO) stroke.Individuals who presented with ...
Michael J. Young +15 more
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Vision, Aphasia, Neglect Assessment for Large Vessel Occlusion Stroke
Journal of Stroke and Cerebrovascular Diseases, 2020Vision, Aphasia, Neglect (VAN) is a large vessel occlusion (LVO) screening tool that was initially tested in a small study where emergency department (ED) nurses were trained to perform VAN assessment on stroke code patients. We aimed to validate the VAN assessment in a larger inpatient dataset.We utilized a large dataset and used National Institute of
Digvijaya Navalkele +6 more
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Endovascular thrombectomy in pediatric patients with large vessel occlusion
Journal of NeuroInterventional Surgery, 2019Background Pediatric acute ischemic stroke with underlying large vessel occlusion is a rare disease with significant morbidity and mortality. There is a paucity of data about the safety and outcomes of endovascular thrombectomy in these cases, especially with modern devices.
Hazem Shoirah +22 more
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Large cerebral vessel occlusive disease in systemic lupus erythematosus
Neurology, 1994We systematically investigated clinical, laboratory, radiologic, and pathologic features, including treatment and prognosis, of stroke syndromes in 30 patients, six from our institution and 24 from the literature, with systemic lupus erythematosus (SLE) and symptomatic large cerebral vessel occlusive disease, documented by angiography or autopsy.
P, Mitsias, S R, Levine
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Occlusion of Large Cerebral Vessels in Sickle-Cell Anemia
New England Journal of Medicine, 1972Abstract Seven patients with sickle-cell anemia and neurologic deficits secondary to Central-nervous-system dysfunction were studied with cerebral angiography after careful preparation. Preparation of the patient reduced the level of S hemoglobin to less than 20 per cent before study, and all studies were performed without sequelae.
J A, Stockman +3 more
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Surgical embolectomy for large vessel occlusion of anterior circulation
British Journal of Neurosurgery, 2013The aim of this study was to assess the technical details and the efficacy and safety of surgical embolectomy for occlusion of large vessels in the anterior circulation.Twenty-three consecutive patients with acute ischemic stroke attributed to embolic occlusion of large arteries of the anterior circulation who underwent treatment with surgical ...
Tomohiro, Inoue +4 more
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Large Vessel Occlusion in Acute Stroke.
Stroke, 2019Background and Purpose- To date, no clinical score has become widely accepted as an eligible prehospital marker for large vessel occlusion (LVO) and the need of mechanical thrombectomy (MT) in ischemic stroke. On the basis of pathophysiological considerations, we propose that cortical symptoms such as aphasia and neglect are more sensitive indicators ...
Lena-Alexandra, Beume +7 more
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Large Vessel Occlusion With Vasculitis in Systemic Lupus Erythematosus
Southern Medical Journal, 1991Patients with SLE may have acute large vessel occlusion due to vasculitis and/or circulating antiphospholipid antibodies, as illustrated by the case we have reported. Unfortunately, delayed medical attention led to gangrene of the foot and amputation.
S M, Harmon, K L, Oltmanns, K W, Min
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