Results 101 to 110 of about 7,488,458 (210)

Putative lotilaner/milbemycin‐induced Stevens‐Johnson syndrome/toxic epidermal necrolysis in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Stevens‒Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe skin and mucocutaneous reaction, characterised by extensive epidermal necrosis and skin sloughing. Drugs are common triggers, with reactions to a number of classes reported.
Matt McHale, Liam Wilson, Tim Nuttall, Victoria Robinson   +3 more
wiley   +1 more source

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Large Vessel Vasculitis and Kawasaki Disease in Japan

, 2010
Based on studies comparing the prevalence of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) between Japan and Europe, we have learned that the difference may be due to genetic background and environmental factors, but not to ...
Shigeto Kobayashi, Kazuo Suzuki, Kei Takahashi, Shouichi Fujimoto   +3 more
core   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

IgG4 Related Disease, A Case of Large Vessel Vasculitis

, 2018
This report describes a case of large vessel vasculitis highlighting diagnostic and therapeutic challenges. It describes the use of the B cell depleting agent Rituximab in this setting.
Ghazi Al Qatari, S, Murphy, G, O’Sullivan, A   +2 more
core  

Use of FDG-PET scan for the assessment of large vessel vasculitis

, 2016
Temporal artery biopsy will only detect (part of) the cranial forms of giant cell arteritis. For the large vessel variant of this type of vasculitis, FDG-PET is the technique of choice.
Blockmans, Daniel Engelbert
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2057-2067, October 2026.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Real‐World Use of Avacopan in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Early and Long‐Term Clinical, Renal, and Patient‐Reported Outcomes in an Italian Rheumatology–Nephrology Network

ACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective Complement activation, particularly through the C5a–C5a receptor axis, plays a pivotal role in the pathogenesis of antineutrophil cytoplasmic antibody–associated vasculitis (AAV) and may represent an important therapeutic target. Avacopan, an oral C5a receptor antagonist, was the first therapy targeting this pathway to enter in clinical ...
Luca Quartuccio, Elena Treppo, Miriam Isola, Maria De Martino, Chiara Marvisi, Luca Iorio, Alessandra Milanesi, Luca Moroni, Edoardo Conticini, Stefania Affatato, Maria Letizia Urban, Enrico Tombetti, Fabio Barone, Pasquale Esposito, Florenzo Iannone, Valentina Binda, Giuseppe Castellano, Corrado Murtas, Lida Tartaglione, Francesco Delle Monache, Amelia Rigon, Maria Chiara Panini, Marco Allinovi, Augusto Vaglio, Bruno Frediani, Paolo Delvino, Sara Monti, Roberto Padoan, Carlomaurizio Montecucco, Lorenzo Dagna, Giacomo Emmi, Federico Alberici, Carlo Salvarani, on behalf of the Italian Society of Rheumatology (Vasculitis and Polymyalgia Rheumatica Study Group)   +33 more
wiley   +1 more source

Prospective Diagnostic Accuracy of Focused Frontal‐Branch Ultrasonography in Giant Cell Arteritis

ACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective To evaluate the diagnostic accuracy, reproducibility, and acquisition time of focused bilateral frontal‐branch ultrasonography based on intima‐media thickness (IMT) in suspected giant cell arteritis (GCA). Methods In this prospective single‐center study, 171 patients underwent color Doppler ultrasonography of the temporal and large arteries ...
Giuseppe Germanò, Carlo Salvarani, Gianluigi Bajocchi, Luigi Boiardi, Maria Grazia Orlando, Alberto Cavazza, Pierluigi Macchioni   +6 more
wiley   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, Volume 15, Issue 39, 23 October 2026.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, Volume 15, Issue 38, 16 October 2026.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source