Results 121 to 130 of about 13,747 (240)

Therapeutic Bark Gouging as an Effective Complement for the Management of Ips typographus and Pityogenes chalcographus While Preserving Habitat for Secondary Scolytine (Coleoptera: Curculionidae) Species

open access: yesJournal of Applied Entomology, Volume 150, Issue 6, Page 780-790, July 2026.
ABSTRACT Norway spruce will likely remain an important tree species in Europe over the next few decades despite efforts to transform forests and reduce its distribution range more to its natural range. Consequently, Ips typographus will remain one of the most relevant forest pests the management of which will become increasingly challenging due to ...
Tobias Frühbrodt   +2 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, Volume 16, Issue 6, Page 1087-1101, June 2026.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

open access: yesAdvanced Science, Volume 13, Issue 31, 4 June 2026.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu   +7 more
wiley   +1 more source

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong   +8 more
wiley   +1 more source

Nursery Rearing of Endangered Mangrove Fish Datnioides polota: Effects of Stocking Density on Growth and Survival

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT The silver tigerfish (Datnioides polota) is an endangered species with high ecological and ornamental value, yet its nursery‐rearing techniques remain underdeveloped, posing a significant challenge for conservation and sustainable aquaculture.
Saima Sultana Sonia   +3 more
wiley   +1 more source

Comparative Phytochemical Analysis of Five South African Bulbine Species Using Chromatography‐Based Methods

open access: yesChemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Comprehensive chromatographic and chemometric profiling of five medicinal South African Bulbine species across leaves, rhizomes, and roots reveals 73 metabolites, including species‐specific phenylanthraquinones, flavonoids, and anthocyanins, that serve as reliable chemical markers for species authentication.
Ramoagi T. Segone   +7 more
wiley   +1 more source

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