Results 191 to 200 of about 34,076 (280)

Structure‐Guided Design of an Interface‐Derived Inhibitor Peptide Against Spodoptera frugiperda Digestive Trypsins

open access: yesArchives of Insect Biochemistry and Physiology, Volume 122, Issue 1, May 2026.
In this study, a rational in silico strategy was employed to design a bioinsecticidal peptide targeting the digestive trypsins of Spodoptera frugiperda, utilizing the Dioscorin–trypsin interface as a structural template. By identifying critical interface hot‐spot residues, an 11‐residue oligopeptide designated as PEP‐11 was engineered, demonstrating ...
José Severiche‐Castro   +2 more
wiley   +1 more source

Cedrela fissilis Vell. Inner Bark: LC–MS/MS‐Based Chemical Profiling and Toxicological Effects

open access: yesChemistry &Biodiversity, Volume 23, Issue 5, May 2026.
ABSTRACT Investigating the mechanistic toxicity of plant extracts is essential for safety assessment. The predictive toxicological effects of Cedrela fissilis were evaluated, and LC–MS/MS‐based chemical profiling was performed. The hydroethanolic extract (HeECf) and ethyl acetate (EA) fraction were assessed in multimodel systems with different levels ...
Thainá Pereira da Silva Cabral   +10 more
wiley   +1 more source

Hydatid Cyst of the Thyroid Gland With Concurrent Hepatic Involvement: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Hydatidosis, caused by Echinococcus granulosus, most commonly affects the liver and lungs, while thyroid involvement is exceptionally rare and can mimic other cystic thyroid lesions. We report a 40‐year‐old woman with no history of animal exposure who presented with anterior neck swelling, odynophagia, and abdominal discomfort. She had a prior
Hana Saffar, Aysan Nozheh, Maral Edalati
wiley   +1 more source

All the bedroom's a stage: Reconceptualizing sex as “performance” to sex as “rehearsal”

open access: yesFeminist Anthropology, Volume 7, Issue 1, May 2026.
Abstract In the United States, sex is often spoken about in terms of performance, and naturally invokes language of theatricality. Sexual performance has been used as an umbrella term to refer to sexual satisfaction, behavior, embodiment, and also pathology in terms of conditions such as erectile dysfunction.
Taylor Harmon
wiley   +1 more source

Tetrandrine, a Major Alkaloid From Stephaniae Tetrandrae Radix, Ameliorates Non‐Alcoholic Fatty Liver Disease in Zebrafish via the PI3K/AKT/STAT3 Pathway

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Tet regulates lipid metabolism and cell apoptosis to alleviate NAFLD. Integrated network pharmacology, Mendelian randomization, and experimental validation demonstrate that Tet activates the PI3K/AKT/STAT3 signaling axis, suppresses apoptosis, reduces hepatic lipid accumulation, and improves biochemical liver injury markers, supporting its potential as
Peng Sun   +11 more
wiley   +1 more source

Pastinaca sativa L.: Nutritional Composition, Phytochemistry, and Pharmacological Properties Supporting Its Potential as a Functional Food and Therapeutic Agent

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Food‐grade processing of Pastinaca sativa (parsnip) converts a nutrient‐rich plant matrix (dietary fiber, fructans, phenolics) through washing/slicing/enzymatic treatment and ingredient preparation into functional food ingredients, including fiber concentrates, antioxidant‐rich fractions, and parsnip powders/extracts.
Somanjana Khatua   +7 more
wiley   +1 more source

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