Results 41 to 50 of about 67,352 (288)

A Pilot Study on Immunohistochemical Expressions of NF-ĸB, Cyclin-D1, VEGF, and Cox-2 in Advanced Stage Laryngeal Carcinoma

Indonesian Biomedical Journal, 2021
BACKGROUND: Progression of laryngeal carcinoma can be classified with the clinical staging, however there are different patterns of progressions observed in the patient with the same clinical stage which also affects their prognoses. Therefore biomarkers
Pudji Rahaju, Ayunita Tri Wirattami, Ferry Sandra, Steffi Kurniawan, Khairun Nisa, Soehartono Soehartono, Edi Handoko, Ahmad Dian Wahyudiono, Hendradi Surjotomo, Hendy Setyo Yudhanto, Nanik Setjowati   +10 more
doaj   +1 more source

Laryngeal Preservation Strategies in Locally Advanced Laryngeal and Hypopharyngeal Cancers. [PDF]

, 2019
For long, the treatment of locoregionally advanced laryngeal and hypopharyngeal squamous cell cancers (SCC) consisted of either total laryngectomy (TL) or definitive radiotherapy (RT).
Argiris, Athanassios, Lefebvre, Jean Louis   +1 more
core   +2 more sources

Tea and coffee consumption and risk of laryngeal cancer: a systematic review meta-analysis.

PLoS ONE, 2014
BackgroundTea and coffee are the most commonly consumed beverages in the worldwide. The relationship between tea and coffee consumption on the risk of laryngeal cancer was still unclear.MethodsRelevant studies were identified by searching electronic ...
Jiangbo Chen, Shuo Long
doaj   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

Annals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya, Koichi Yagi, Yoshifumi Baba   +2 more
wiley   +1 more source

Maintenance of head and neck tumor on-chip: gateway to personalized treatment? [PDF]

, 2017
Aim: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40–60%). In a move toward personalized medicine, maintenance of tumor biopsies in microfluidic tissue culture devices is being developed. Methodology/ results:
Bower, Ruth, Crank, Stephen T, Green, Victoria L., Greenman, John, Karsai, Laszlo, Kuvshinov, Dmitriy, Kuvshinova, Elena, Stafford, Nicholas D   +7 more
core   +1 more source

Extent of Lymph Node Dissection for cStage I Siewert Type I/II Cancers Based on Lymph Node Metastasis Risk Stratification

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The optimal surgical strategy and extent of lymph node (LN) dissection for clinical Stage I (cStage I) adenocarcinoma of the esophagogastric junction (AEG) remain controversial. This study aimed to evaluate surgical outcomes and clarify the prevalence and distribution of LN metastasis according to tumor characteristics in cStage I Siewert ...
Masayoshi Terayama, Akihiko Okamura, Tomoyuki Irino, Naoki Takahashi, Jun Kanamori, Yu Imamura, Masaru Hayami, Motonari Ri, Souya Nunobe, Masayuki Watanabe   +9 more
wiley   +1 more source

Inhibitory Effect of miRNA let-7a on Proliferation of Human Laryngeal Squamous Cell Carcinoma

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate how miRNA let-7a targets high-mobility AT-hook 2 (HMGA2) and suppresses the proliferation of laryngeal carcinoma cell line TU212.
MA Lijuan, ZHOU En, ZOU Lianhong, YIN Juan, XIAO Xuping   +4 more
doaj   +1 more source

Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic devices [PDF]

, 2013
Objective The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment.
Burcombe R, Cai L, Eriksson D, Eriksson D, Fernberg JO, Hattersley SM, Hattersley SM, Ianzini F, Jemal A, Kamotani Y, Kroemer G, Lee P, Ma H, Mamouni J, Mansilla S, Mauk MG, Mirzaie-Joniani H, Mulhall HJ, Nevill JT, Parkin DM, Reddy AC, Remmerbach TW, Skoda C, Ts’ao C, Weigum SE, Withrow KP, Young EW, Ziober BL   +27 more
core   +2 more sources

Potential Survival Benefit of Neoadjuvant Docetaxel, Cisplatin and 5‐Fluorouracil Therapy in Patients With Esophageal Squamous Cell Carcinoma With Multiple Lymph Node Metastases: A Single‐Institute Propensity Score Analysis

Annals of Gastroenterological Surgery, EarlyView.
Although neoadjuvant chemotherapy with fluorouracil, cisplatin, and docetaxel (NAC‐DCF) is the current standard neoadjuvant regimen for esophageal squamous cell carcinoma, its substantial toxicity underscores the need to identify patients who derive the greatest benefit.
Eiji Higaki, Tetsuya Abe, Hironori Fujieda, Shigenori Kadowaki, Tsutomu Tanaka, Masahiro Tajika, Koji Komori, Seiji Ito, Isao Oze, Kei Muro   +9 more
wiley   +1 more source

Image findings of cranial nerve pathology on [18F]-2- deoxy-D-glucose (FDG) positron emission tomography with computerized tomography (PET/CT): a pictorial essay. [PDF]

, 2015
This article aims to increase awareness about the utility of (18)F -FDG-PET/CT in the evaluation of cranial nerve (CN) pathology. We discuss the clinical implication of detecting perineural tumor spread, emphasize the primary and secondary (18)F -FDG-PET/
Muzaffar, Razi, Osman, Medhat M, Raslan, Osama A, Shetty, Vilaas   +3 more
core   +1 more source